Evidence map›Paper›PMID 35173197›Full record

ArticleScientific reports2022

A machine learning model for predicting deterioration of COVID-19 inpatients.

Omer Noy, Dan Coster, Maya Metzger, Itai Atar, Shani Shenhar-Tsarfaty, Shlomo Berliner, Galia Rahav, Ori Rogowski, Ron Shamir

Open access · goldAbstract readValidation Study
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Omer Noy *Blavatnik School of Computer Science, Tel-Aviv University, 30 Haim Levanon Street, 69978, Tel Aviv, Israel.
Dan Coster *Blavatnik School of Computer Science, Tel-Aviv University, 30 Haim Levanon Street, 69978, Tel Aviv, Israel.
Maya MetzgerBlavatnik School of Computer Science, Tel-Aviv University, 30 Haim Levanon Street, 69978, Tel Aviv, Israel.
Itai AtarSackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Shani Shenhar-TsarfatySackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Shlomo BerlinerSackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Galia RahavSackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Ori RogowskiSackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Ron ShamirBlavatnik School of Computer Science, Tel-Aviv University, 30 Haim Levanon Street, 69978, Tel Aviv, Israel. rshamir@tau.ac.il.
Tel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has been spreading worldwide since December 2019, presenting an urgent threat to global health. Due to the limited understanding of disease progression and of the risk factors for the disease, it is a clinical challenge to predict which hospitalized patients will deteriorate. Moreover, several studies suggested that taking early measures for treating patients at risk of deterioration could prevent or lessen condition worsening and the need for mechanical ventilation. We developed a predictive model for early identification of patients at risk for clinical deterioration by retrospective analysis of electronic health records of COVID-19 inpatients at the two largest medical centers in Israel. Our model employs machine learning methods and uses routine clinical features such as vital signs, lab measurements, demographics, and background disease. Deterioration was defined as a high NEWS2 score adjusted to COVID-19. In the prediction of deterioration within the next 7-30 h, the model achieved an area under the ROC curve of 0.84 and an area under the precision-recall curve of 0.74. In external validation on data from a different hospital, it achieved values of 0.76 and 0.7, respectively.

Indexed as

Clinical DeteriorationCOVID-19Machine LearningModels, StatisticalHumansRetrospective StudiesSoftware

Identifiers

PMID35173197
PMCPMC8850417
OpenAlexW4212770270

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.