Evidence map›Paper›PMID 35173181›Full record

ArticleScientific reports2022

Evaluating the role of propolis and bee venom on the oxidative stress induced by gamma rays in rats.

Eithar K El Adham, Amal I Hassan, M M A Dawoud

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 57 citations in OpenAlex.

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  14. Pharmacological properties and therapeutic potential of honey bee venom.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Eithar K El AdhamRadioisotopes Department, Nuclear Research Center, Egyptian Atomic Energy Authority, Dokki, Giza, 12311, Egypt.
Amal I HassanRadioisotopes Department, Nuclear Research Center, Egyptian Atomic Energy Authority, Dokki, Giza, 12311, Egypt. virtualaml@gmail.com.
M M A DawoudRadioisotopes Department, Nuclear Research Center, Egyptian Atomic Energy Authority, Dokki, Giza, 12311, Egypt.
Egyptian Atomic Energy Authority · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Honeybee products consist of many substances, which have long been known for their medicinal and health-promoting properties. This study set out to appraise the protective potential of Egyptian propolis (EP) and bee venom (BV) separately or combined against total body irradiation (TBI) induced oxidative injury in rats. Besides, we assessed the bioactive components in EP and BV using HPLC and UPLC/ ESI-MS analysis in the positive ion mode. The animals were subjected to a source of gamma ionizing radiation at a dose of 6 Gy. Propolis and BV were administered independently and in combination before 14 days of γ-irradiation. Liver and kidney functions were estimated besides, DNA damage index (8- OHdG) by ELISA. Antioxidants, including glutathione (GSH), catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPx) were detected. Gene expression technique investigated for BAX, BCL2, and in plasma also miR125b expression in serum of rats. Besides, the histopathological for the brain, liver, kidney, and heart were investigated. In addition, lipid peroxidation was investigated in plasma and in the previous organs. The present results provide opportunities to advance the use of bee products as promising medicinal sources.

Indexed as

Radiation-Protective AgentsAnimalsAntioxidantsbcl-2-Associated X ProteinBee VenomsDNA DamageGamma RaysIn Vitro TechniquesOxidative StressPropolisProto-Oncogene Proteins c-bcl-2RatsTumor Suppressor Protein p53AntioxidantsBax protein, ratbcl-2-Associated X ProteinBcl2 protein, ratBee VenomsPropolisProto-Oncogene Proteins c-bcl-2Radiation-Protective AgentsTumor Suppressor Protein p53

Identifiers

PMID35173181
PMCPMC8850618
OpenAlexW4213135281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.