Evidence map›Paper›PMID 35172912›Full record

ArticleEpidemiology and infection2021

Seroepidemiology of SARS-CoV-2 infections in an urban population-based cohort in León, Nicaragua.

Fredman González, Nadja A Vielot, Michael Sciaudone, Christian Toval-Ruíz, Lakshmanane Premkumar, Lester Gutierrez, Edwing Centeno Cuadra, Nancy Munguia, Patricia Blandón, Aravinda M de Silva and 4 more

Open access · goldAbstract read
In one paragraph

Article in Epidemiology and infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Clinical Spectrum of Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Protection From Symptomatic Reinfection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  8. Article
  9. Article
  10. Burden of SARS-CoV-2 and protection from symptomatic second infection in children.medRxiv : the preprint server for health sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Fredman GonzálezCenter for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
Nadja A VielotDepartment of Family Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-9004-0609
Michael SciaudoneDivision of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Christian Toval-RuízCenter for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
Lakshmanane PremkumarDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Lester GutierrezCenter for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
Edwing Centeno CuadraCenter for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
Nancy MunguiaCenter for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
Patricia BlandónCenter for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
Aravinda M de SilvaDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Rebecca RubinsteinSchool of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Natalie BowmanDivision of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Sylvia Becker-DrepsDepartment of Family Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Filemon BucardoCenter for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.
National Autonomous University of Nicaragua · NIUniversity of North Carolina at Chapel Hill · US

Funding

Natural history, immunity, and transmission patterns of sapovirus in a Nicaraguan birth cohortR01AI127845 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BECKER-DREPS, SYLVIA IRENE, VINJE, JAN · 2016 to 2020
$3.5M
Understanding protection against norovirus at the maternal-child interfaceK24AI141744 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Sylvia Irene Becker-Dreps · 2019 to 2026
$1.4M
Nicaraguan Emerging and Endemic Diseases (NEED) Training ProgramD43TW010923 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BECKER-DREPS, SYLVIA IRENE · 2018 to 2023
$1.4M
FIC NIH HHS D43 TW010923NIAID NIH HHS K24 AI141744NIAID NIH HHS R01 AI127845
6 · The paper itself

Abstract

In a Nicaraguan population-based cohort, SARS-CoV-2 seroprevalence reached 28% in the first 6 months of the country's epidemic and reached 35% 6 months later. Immune waning was uncommon. Individuals with a seropositive household member were over three times as likely to be seropositive themselves, suggesting the importance of household transmission.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolCohort StudiesCOVID-19FemaleHumansMaleMiddle AgedNicaraguaPrevalenceSARS-CoV-2Seroepidemiologic StudiesCOVID-19epidemiologyNicaraguaSARS-CoV-2seroprevalence

Identifiers

PMID35172912
PMCPMC8674192
OpenAlexW3206527406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.