ArticleBMC surgery2022
Frailty index is useful for predicting postoperative morbidity in older patients undergoing gastrointestinal surgery: a prospective cohort study.
Article in BMC surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06281275 (A Study on the Association Between Frailty and Acute Postoperative Pain in Elderly Patients Undergoing Thoracoscopic Surgery and an Investigation of the Mechanisms Involved), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Study on the Association Between Frailty and Acute Postoperative Pain in Elderly Patients Undergoing Thoracoscopic Surgery and an Investigation of the Mechanisms Involved
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Risk factors for preoperative frailty in older patients with gastric cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Frailty and low utilization of curative-intent surgical resection in nonmetastatic pancreatic cancer.JNCI cancer spectrum · 2026Article
- Short-term safety and efficacy of revision or conversion metabolic and bariatric surgery in older adults: an analysis of the MBSAQIP database.Surgical endoscopy · 2026Article
- Decision making in chronic subdural haematoma patient referrals in an octogenarian and nonagenarian population - a multi-centre perspective.Irish journal of medical science · 2026Article
- Relationship between preoperative modified frailty index, immune-inflammation index, and outcomes of colorectal cancer surgery in older patients.World journal of gastrointestinal oncology · 2026Article
- Poor Sleep Quality Associated with Impaired Postoperative Outcomes and Frailty Incidence in Elderly Patients After Total Hip Arthroplasty: A Severity Matched Case-Control Study.Journal of multidisciplinary healthcare · 2026Article
- Impact of Preoperative Frailty on Postoperative Complications and Cognitive Impairment in Liver Cancer Patients: An Observational Cohort Study.Clinical interventions in aging · 2026Observational
- Frailty and Time-To-Theatre for Elderly Hip Fracture Patients at a Regional Hospital in Australia: A Retrospective Cohort Study.Geriatric orthopaedic surgery & rehabilitation · 2026Article
- External validation of an AI-based preoperative frailty index using real-world data.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Frailty as an Independent predictor of perioperative risk and recovery in long-segment thoracolumbar fusion surgery: A retrospective cohort study.North American Spine Society journal · 2025Article
- Same Day Discharges Among Elderly Mastectomy Patients: A Single Institution Prospective Study.Annals of surgical oncology · 2025Article
- Optimizing Perioperative Care in Esophageal Surgery: The EUropean PErioperative MEdical Networking (EUPEMEN) Collaborative for Esophagectomy.Diseases (Basel, Switzerland) · 2025Article
- Evaluation of the correlation between pre-anaesthetic P-POSSUM score, ultrasound muscle assessment and frailty index on perioperative outcome - An observational trial.Indian journal of anaesthesia · 2025Article
- Construction and validation of a risk prediction model for postoperative frailty in older adults:a multicenter study.BMC geriatrics · 2025Article
- Factors associated with frailty status compared to pre-frailty in community-dwelling older adults: a cross-sectional study.Frontiers in public health · 2025Article
- Comparison of Modified Frailty Index, Clinical Frailty Scale, ECOG Score, and ASA PS Score in Predicting Postoperative Outcomes in Cancer Surgery: A Prospective Study.Indian journal of surgical oncology · 2024Article
- Article
- Development of a Frailty Index in the Irish Hip Fracture Database.Archives of orthopaedic and trauma surgery · 2023Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundMany assessment tools have been used to identify frail surgical patients. This study was designed to explore the prediction value of the frailty index (FI) for postoperative morbidity in older patients undergoing elective gastrointestinal surgery.
methodsBetween January 2019 and September 2020, we conducted a prospective study in our hospital, and patients aged over 65 years were enrolled. The FI assessment was conducted by two specialist nurses based on the 38-item scale, and patients were considered frail if the FI score was ≥ 0.25. The primary outcome was 30-day postoperative morbidity. Univariable and multivariable analyses were used to find the risk factors related to postoperative morbidity.
resultsA total of 246 consecutive patients were enrolled, for whom the median age was 72.0 [interquartile range (IQR): 67.0-77.0] years old, and 175 (71.1%) were male. Of these, 47 (19.1%) were frail. Patients with frailty were associated with older age (p < 0.001), higher American Society of Anesthesiologists (ASA) grade (p = 0.006), lower body mass index (p = 0.001), lower albumin (p = 0.003) and haemoglobin (p < 0.001) levels, increased blood loss (p = 0.034), increased risk of postoperative morbidity (p < 0.001), increased median length of stay (p = 0.017), and increased median postoperative hospital stay (p = 0.003). Multivariable analysis revealed that ASA grade [odds ratio (OR): 2.59, 95% confidence interval (CI) 1.19-5.64, p = 0.016], FI score (OR 7.68, 95% CI 3.19-18.48, p < 0.001) and surgical complexity (OR 22.83, 95% CI 5.46-95.51, p < 0.001) were independent predictors of 30-day postoperative morbidity. However, for patients with major surgery, FI score was the only independent predictor (OR 8.67, 95% CI 3.23-23.25, p < 0.001).
conclusionFrailty was associated with adverse perioperative outcomes, and the 38-item FI scale was a useful frailty screening tool for older patients undergoing elective gastrointestinal surgery. For patients with major surgery, frailty was a more reliable predictor of postoperative 30-day morbidity than age and ASA grade.
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