ArticleAmyotrophic lateral sclerosis & frontotemporal degeneration2022
Clinical trials in pediatric ALS: a TRICALS feasibility study.
Open access · hybridAbstract read
In one paragraph
Article in Amyotrophic lateral sclerosis & frontotemporal degeneration, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Exploring amyotrophic lateral sclerosis through the visual system: A systematic review.European journal of neurology · 2024Pooled it
- Acquired hemophilia a in a female with minimal change disease and hypothyroidism: a rare case report.Annals of medicine and surgery (2012) · 2025Article
- Did pediatric drug development advance epilepsy treatment in young patients? It is time for new research goals.World journal of methodology · 2024Review
- Utility of exome sequencing for the diagnosis of pediatric-onset neuromuscular diseases beyond diagnostic yield: a narrative review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Review
- Clinical and Genetic Aspects of Juvenile Amyotrophic Lateral Sclerosis: A Promising Era Emerges.Genes · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
57 authors at 20 institutions in 19 countries.
Tessa KliestDepartment of Neurology, UMC Utrecht Brain Centre, University Medical Centre Utrecht, Utrecht, the Netherlands.
Ruben P A Van EijkDepartment of Neurology, UMC Utrecht Brain Centre, University Medical Centre Utrecht, Utrecht, the Netherlands.
Ammar Al-ChalabiDepartment of Basic and Clinical Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.ORCID 0000-0002-4924-7712
Alberto AlbaneseIRCCS Humanitas Research Hospital Rozzano, Milan, Italy.
Peter M AndersenDepartment of Clinical Sciences, Neurosciences, Umeå University, Umeå, Sweden.
Maria Del Mar AmadorDépartement de Neurologie, Centre de référence SLA Ile de France.
Geir BrÅthenDepartment of Neurology, University Hospital of Trondheim, Trondheim, Norway.
Veronique Brunaud-DanelALS centre, CHU, University of Lille Nord de France, Lille, France.
Lev BrylevBujanov Moscow City Clinical Hospital, Moscow, Russian Federation.ORCID 0000-0003-2314-6523
William CamuALS Centre CHU Gui de Chauliac, University of Montpellier, Montpellier, France.
Mamede De CarvalhoInstitute of Physiology-Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.ORCID 0000-0001-7556-0158
Cristina CeredaRegional Newborn Screening Laboratory, Vittore Buzzi Children's Hospital-University of Milan, Italy.
Hakan CetinDepartment of Neurology, Medical University of Vienna, Vienna, Austria.
Delia ChaverriNeurology Service, Hospital Universitario La Paz, Madrid, Spain.
Adriano Chiò'Rita Levi Montalcini' Department of Neuroscience, ALS Centre, University of Torino, Turin, Italy.ORCID 0000-0001-9579-5341
Philippe CorciaCentre Constitutif SLA, CHRU de Tours - Fédération des centres SLA Tours-Limoges, LitORALS, Tours, France.ORCID 0000-0002-1625-8845
Philippe CouratierCentre Constitutif de reference SLA-Fédération Tours-Limoges, CHU de Limoges, Limoges, France.
Fabiola De Marchi"Maggiore della Carità" University Hospital, Novara, Italy.
Claude DesnuelleHôpital Pasteur 2 - CHU de Nice, Nice, France.
Michael A Van EsDepartment of Neurology, UMC Utrecht Brain Centre, University Medical Centre Utrecht, Utrecht, the Netherlands.
JesÚs EstebanALS Research Lab - ALS Unit, Instituto de Investigación Sanitaria Hospital 12 de Octubre "i + 12", CIBERER, Madrid, Spain.
Massimiliano FilostoDepartment of Clinical and Experimental Sciences, University of Brescia; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.ORCID 0000-0002-2852-7512
Alberto GarcÍa RedondoALS Research Lab - ALS Unit, Instituto de Investigación Sanitaria Hospital 12 de Octubre "i + 12", CIBERER, Madrid, Spain.
Julian GrosskreutzPrecision Neurology, Dept. of Neurology, Lübeck University Hospital, Lübeck, Germany.
Clemens O HanemannUniversity of Plymouth, Peninsula Schools of Medicine and Dentistry, Plymouth, UK.ORCID 0000-0002-1951-1025
Trygve HolmØyDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.
Helle HØyerDepartment of Medical Genetics, Telemark Hospital, Skien, Norway.
Caroline IngreDepartment of Neurology, Karolinska University Hospital, Stockholm, Sweden.
Blaz KoritnikInstitute of Clinical Neurophysiology, University Medical Centre Ljubljana, Ljubljana, Slovenia.ORCID 0000-0002-5083-8261
Magdalena Kuzma-KozakiewiczDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Thomas LambertDepartment of Neurology, Royal Stoke University Hospital, Stoke, United Kingdom.
Peter N LeighDepartment of Neuroscience, Brighton and Sussex Medical School, Trafford Centre for Biomedical Research, University of Sussex, Brighton, UK.
Christian LunettaNEMO Clinical Center, Serena Onlus Foundation, Milan, Italy.
Jessica MandrioliDepartment of Biomedical, Metabolic and Neural Sciences, Center for Neuroscience and Neurotechnology, University of Modena and Reggio Emilia, Modena, Italy.
Christopher J McdermottDepartment of Neuroscience, University of Sheffield, Sheffield Institute for Translational Neuroscience, Sheffield, United Kingdom.ORCID 0000-0002-1269-9053
Thomas MeyerALS Outpatient Department, Charité - Universitatsmedizin Berlin, Berlin, Germany.
Jesus S MoraALS Unit/Neurology, Hospital San Rafael, Madrid, Spain.
Susanne PetriDepartment of Neurology, Hannover Medical School, Hannover, Germany.
MÓnica PovedanoFunctional Unit of Amyotrophic Lateral Sclerosis (UFELA), Service of Neurology, Bellvitge University Hospital, Hospitalet de Llobregat, Spain.
Evy ReviersEuropean Organization for Professionals and Patients with ALS (EUpALS) & ALS Liga Belgium, Leuven, Belgium.
Nilo RivaDepartment of Neurology, Experimental Neuropathology Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy.
Kit C B RoesDepartment of Health Evidence, Section Biostatistics, Radboud University Medical Centre Nijmegen, Nijmegen, the Netherlands.
Miguel Á RubioNeuromuscular Unit, Department of Neurology, Hospital del Mar, Barcelona, Spain.
FranÇois SalachasDépartement de Neurologie, Centre de référence SLA Ile de France.
Stayko SarafovClinic of General Neurology, Medical University Sofia, University Hospital Alexandrovska, Sofia, Bulgaria.
Gianni SorarÙDepartment of Neurosciences, University of Padova, Padova, Italy.
Zorica StevicClinic of Neurology, Clinical Center of Serbia, School of Medicine, University of Belgrade, Belgrade, Serbia.
Kirsten SvenstrupDepartment of Neurology, Bispebjerg-Frederiksberg Hospital and Rigshospitalet, University Hospital of Copenhagen, Denmark.
Anette Torvin MØllerDepartment of Neurology, Aarhus University Hospital, Aarhus, Denmark.
Martin R TurnerNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.ORCID 0000-0003-0267-3180
Philip Van DammeDepartment of Neurosciences, Laboratory for Neurobiology, KU Leuven and Centre for Brain & Disease Research, VIB, Leuven Brain Institute, Leuven, Belgium.ORCID 0000-0002-4010-2357
Lucie A G Van LeeuwenDepartment of Neurology, UMC Utrecht Brain Centre, University Medical Centre Utrecht, Utrecht, the Netherlands.
Luis VaronaDepartment of Neurology, Basurto University Hospital, Vizcaya, Spain.
Juan F VÁzquez CostaALS Unit and Neuromuscular Disease Unit, Department of Neurology, Hospital La Fe, Valencia, Spain.ORCID 0000-0002-3043-7938
Markus WeberNeuromoscular Disease Unit/ALS Clinic, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
Orla HardimanAcademic Unit of Neurology Trinity College Dublin Ireland, Dublin, Ireland.
Leonard H Van Den BergDepartment of Neurology, UMC Utrecht Brain Centre, University Medical Centre Utrecht, Utrecht, the Netherlands.
University Medical Center Utrecht · NLCentre Hospitalier Universitaire de Tours · FRResearch Institute Hospital 12 de Octubre · ESSorbonne Université · FRAarhus University Hospital · DKAlexandrovska Hospital · BGAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITBellvitge University Hospital · ESBrighton and Sussex Medical School · GBCentre Hospitalier Universitaire de Nice · FRCentro Clinico Nemo · ITCharité - Universitätsmedizin Berlin · DEFrederiksberg Hospital · DKHospital de Basurto · ESHospital Del Mar · ESHospital Universitario La Paz · ESHospital Universitario San Rafael · ESIRCCS Humanitas Research Hospital · ITKarolinska University Hospital · SEKing's College London · GB
Funding
Department of HealthMedical Research Council MR/L501529/1Medical Research Council MR/R024804/1Motor Neurone Disease Association ALCHALABI-TALBOT/APR14/926-794Motor Neurone Disease Association TURNER/OCT18/989-797
Abstract
PubMed holds no abstract for this paper.
Indexed as
Amyotrophic Lateral SclerosisAdultChildDatabases, FactualEuropeFeasibility StudiesHumansPrevalenceclinical trialclinical trialsethicsPediatric amyotrophic lateral sclerosispediatric investigation plantherapy
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.