Evidence map›Paper›PMID 35172607›Full record

ArticleStroke2022

Racial Inequities Across Rural Strata in Acute Stroke Care and In-Hospital Mortality: National Trends Over 6 Years.

Gmerice Hammond, R J Waken, Daniel Y Johnson, Amytis Towfighi, Karen E Joynt Maddox

Erratum issuedAbstract read
In one paragraph

Article in Stroke, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Hospital Socioeconomic Status and Acute Stroke Treatment in the United States.Cerebrovascular diseases (Basel, Switzerland) · 2026
    Article
  3. Racial and ethnic disparities in access to acute stroke capabilities in California: Association with rurality and telestroke access.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. THE ROLE OF HEALTH POLICY IN IMPROVING HEALTH OUTCOMES AND HEALTH EQUITY.Transactions of the American Clinical and Climatological Association · 2024
    Article
  11. Black Americans have worse stroke outcome compared with non-Hispanic whites.Journal of the National Medical Association · 2023
    Article
  12. Racial and Ethnic Disparities in Stroke Reperfusion Therapy in the USA.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Gmerice HammondCardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, MO (C.H., R.J.W., D.Y.J., K.E.J.M.).
R J WakenCardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, MO (C.H., R.J.W., D.Y.J., K.E.J.M.).ORCID 0000-0001-6678-7764
Daniel Y JohnsonCardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, MO (C.H., R.J.W., D.Y.J., K.E.J.M.).
Amytis TowfighiDepartment of Neurology, University of Southern California Keck School of Medicine, Los Angeles (A.T.).ORCID 0000-0002-9565-6787
Karen E Joynt MaddoxCardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, MO (C.H., R.J.W., D.Y.J., K.E.J.M.).ORCID 0000-0003-3779-8653

Funding

PRINCIPLES IN CARDIVASCULAR RESEARCH TRAINING PROGRAMT32HL007081 · NHLBI · WASHINGTON UNIVERSITY · PI Abhinav Diwan, Karen Ellen Joynt Maddox · 1985 to 2026
$10.6M
The Impact of Bundled Payments for Cardiopulmonary Disease on High-Risk PopulationsR01HL143421 · NHLBI · WASHINGTON UNIVERSITY · PI JOYNT MADDOX, KAREN ELLEN · 2019 to 2022
$3.1M
Improving the Quality of Care Provided Through Bundled Payments for Patients with Alzheimer's Disease or Other Forms of Dementia or FrailtyR01AG060935 · NIA · HARVARD SCHOOL OF PUBLIC HEALTH · PI EPSTEIN, ARNOLD, JOYNT MADDOX, KAREN ELLEN · 2019 to 2021
$2.7M
Observation Stays and Readmissions for Older Adults: Implications for Medicare PoliciesR01AG063759 · NIA · UNIVERSITY OF WASHINGTON · PI SABBATINI, AMBER KATHLEEN · 2020 to 2023
$1.4M
The Effect of Patient Dementia on Outpatient Clinicians' Performance on Cost Outcomes Under Medicare Value-Based Payment.R21AG065526 · NIA · WASHINGTON UNIVERSITY · PI JOHNSTON, KENTON JAMES · 2020 to 2021
$308k
NHLBI NIH HHS R01 HL143421NHLBI NIH HHS T32 HL007081NIA NIH HHS R01 AG060935NIA NIH HHS R01 AG063759NIA NIH HHS R21 AG065526
6 · The paper itself

Abstract

backgroundThere are glaring racial and rural-urban inequities in stroke outcomes. The objective of this study was to determine whether there were recent changes to trends in racial inequities in stroke treatment and in-hospital mortality, and whether racial inequities differed across rural strata.

methodsRetrospective analysis of Black and White patients >18 years old admitted to US acute care hospitals with a primary discharge diagnosis of stroke (unweighted N=652 836) from the National Inpatient Sample from 2012 to 2017. Rural residence was classified by county as urban, town, or rural. The primary outcomes were intravenous thrombolysis and endovascular therapy use among patients with acute ischemic stroke, and in-hospital mortality for all stroke patients. Logistic regression models were run for each outcome adjusting for age, comorbidities, primary payer, and ZIP code median income.

resultsThe sample was 53% female, 81% White, and 19% Black. Black patients from rural areas had the lowest odds of receiving intravenous thrombolysis (adjusted odds ratio [aOR], 0.43 [95% CI, 0.37-0.50]) and endovascular therapy (aOR, 0.60 [0.46-0.78]), compared with White urban patients. Black rural patients were the least likely to be discharged home after a stroke compared with White/urban patients (aOR, 0.79 [0.75-0.83]), this was true for Black patients across the urban-rural spectrum when compared with Whites. Black patients from urban areas had lower mortality than White patients from urban areas (aOR, 0.87 [0.84-0.91]), while White patients from rural areas (aOR, 1.14 [1.10-1.19]) had the highest mortality of all groups.

conclusionsBlack patients living in rural areas represent a particularly high-risk group for poor access to advanced stroke care and impaired poststroke functional status. Rural White patients have the highest in-hospital mortality. Clinical and policy interventions are needed to improve access and reduce inequities in stroke care and outcomes.

Indexed as

Ischemic StrokeStrokeAdolescentFemaleHospital MortalityHumansMaleRetrospective StudiesRural Populationadolescentmortalityodds ratiopatient dischargeretrospective studies

Identifiers

PMID35172607
PMCPMC9324215

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.