Evidence map›Paper›PMID 35172074›Full record

ReviewKorean journal of anesthesiology2022

Different perspectives for monitoring nociception during general anesthesia.

Pablo Martinez-Vazquez, Erik Weber Jensen

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Korean journal of anesthesiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07738770 (Analgesic Efficacy Comparison of Combined PECS II and Superficial Parasternal Intercostal Plane), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07738770 narecruitingnot on this mapstarted 2026, after this paper: background citation

Analgesic Efficacy Comparison of Combined PECS II and Superficial Parasternal Intercostal Plane (PIP) Block Versus Thoracic Paravertebral Block Post-Mastectomy: An Assessment of Pain Severity, Analgesia Duration, and Recovery Quality

TypeinterventionalSponsorDharmais National Cancer Center HospitalRan2026 to 2026Enrolled72ConditionsAcute Pain, Post Operative Analgesia, Post Operative Pain, Acute, Breast CancerArmsCombined PECS II and Superficial PIP Block, Thoracic paravertebral block (TPVB)
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pablo Martinez-VazquezFunctional Imaging Laboratory, German Primate Center (DPZ), Goettingen, Germany.
Erik Weber JensenR&D of Quantium Medical/Fresenius Kabi, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Safe anesthesia is achieved using objective methods that estimate the patient's state during different phases of surgery. A patient's state under anesthesia is characterized by three major aspects, which are linked to the main effects produced by each of the families of anesthetic agents administered: hypnosis, analgesia, and muscular relaxation. While quantification techniques designed to assess muscular relaxation under neuromuscular blocking agents have a relatively long history with a high degree of standardization and understanding (e.g., the train-of-four), the knowledge and techniques used to the depth of hypnosis assessment suffer from a lesser degree in both standardization and interpretation due to brain complexity. The problem of standardization and interpretation in the analgesia and nociception assessment increases since it involves more systems, the central nervous system, and the autonomic nervous system. This helps to explain why there are multiple a priori valid approaches to develop nociception monitoring from different interpretations and physiological bases of noxious stimuli processing. Thus, in this review, the current monitoring technologies clinically available for estimating a patient's nociception under general anesthesia are described.

Indexed as

AnalgesiaNociceptionAnesthesia, GeneralHumansMonitoring, IntraoperativePain ManagementAutonomic nervous systemCentral nervous systemElectroencephalographyGalvanic skin responseHeart rateH-ReflexNociception

Identifiers

PMID35172074
PMCPMC8980281

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.