ArticleScience translational medicine2022
Antimicrobial production by perifollicular dermal preadipocytes is essential to the pathophysiology of acne.
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Article in Science translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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0cells of the map it votes in
43citing papers in PubMed
12.5field-weighted citation impact, top 1% of its field
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Who cites it
43 citing papers in PubMed, 64 citations in OpenAlex.
- Emerging bioactive microneedle platforms for disease management: From cutaneous disorders to systemic therapeutics.Bioactive materials · 2026Review
- Acne: epidemiology, risk factors, pathogenesis, management and cutting-edge research.Signal transduction and targeted therapy · 2026Review
- Fibroblasts resistScience advances · 2026Article
- Chessboard Microneedle Array for Inflammation Regulation via Spatiotemporally Controlled Drug Delivery.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Dermal fibroblasts respond to IL-4 and IL-13 and promote T cell recruitment in atopic dermatitis.The Journal of clinical investigation · 2026Article
- Adipocytes as core drivers of skin aging and novel targets for regeneration.Biogerontology · 2026Review
- Spatial transcriptomics identifies differentiation, lipid metabolism, and retinoid pathway alterations in acne vulgaris.JCI insight · 2026Article
- Keratinocyte-Associated Biomarkers Reveal Pathogenic Mechanisms in Acne.FASEB bioAdvances · 2026Article
- Transcriptomic Profiling ofCurrent issues in molecular biology · 2025Article
- T-cell immunoglobulin and mucin domain-containing protein 3-mediated immunomodulation in myeloid cells and keratinocytes in the development of severe acne.Molecular biomedicine · 2025Article
- Dissolved bubble microneedle patches for co-delivery of hydrophobic and hydrophilic drugs to improve acne vulgaris therapy.Microsystems & nanoengineering · 2025Article
- Post-burn Lung Inflammation Is Associated With Induction of Pulmonary Cathelicidin-related Antimicrobial Peptide and S100a8 in Mice.Journal of burn care & research : official publication of the American Burn Association · 2025Article
- Advances in Single-Cell Sequencing for Infectious Diseases: Progress and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Vitamin D and skin disorders: bridging molecular insights to clinical innovations.Molecular medicine (Cambridge, Mass.) · 2025Review
- Insights into microbial dysbiosis andMicrobial genomics · 2025Article
- Antimicrobial Peptide Signaling in Skin Diseases.JID innovations : skin science from molecules to population health · 2025Review
- Psychological stress increases skin infection through the action of TGFβ to suppress immune-acting fibroblasts.Science immunology · 2025Article
- Ultrasound-mediated nanomaterials for the treatment of inflammatory diseases.Ultrasonics sonochemistry · 2025Review
- Acne vulgaris: advances in pathogenesis and prevention strategies.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Review
- Mechanistic insights into 5-aminolevulinic acid photodynamic therapy for acne vulgaris: targeting lipogenesis via the OLR1-Wnt/β-catenin pathway.Molecular medicine (Cambridge, Mass.) · 2025Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Alan M O'NeillDepartment of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-5892-6477
Marc C LigginsDepartment of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-1402-9245
Jason S SeidmanDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0001-7626-5759
Tran H DoDivision of Dermatology, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0001-6317-9202
Fengwu LiDepartment of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0001-5092-770X
Kellen J CavagneroDepartment of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-4160-6394
Tatsuya DokoshiDepartment of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-3678-6781
Joyce Y ChengDepartment of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-7317-7486
Faiza ShafiqDepartment of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0001-6211-7712
Tissa R HataDepartment of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA.
Johann E GudjonssonDepartment of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-0080-0812
Robert L ModlinDivision of Dermatology, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-4720-031X
Richard L GalloDepartment of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-1401-7861
University of California San Diego · USUniversity of California, Los Angeles · USUniversity of Michigan · US
Funding
VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jesse Nodora · 1985 to 2026
$124.9MMolecular Analysis of the Host Immune Response in LeprosyR01AI022553 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROBERT L MODLIN · 1989 to 2026
$15.7MTCR GAMMA/DELTA LYMPHOCYTES IN HUMAN SKIN LESIONSR01AR040312 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MODLIN, ROBERT L · 1990 to 2025
$10.4MMicrobiology and Metagenomics CoreP50AR080594 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROBERT L MODLIN · 2022 to 2026
$9.2MUniversity of Michigan Skin Biology and Diseases Resource-based CenterP30AR075043 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Johann Eli Gudjonsson · 2019 to 2026
$6.6MCathelicidin in Skin ImmunityR37AI052453 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Richard L Gallo, Victor Nizet · 2019 to 2026
$4.6MInflammatory cross-talk between skin and gutR01DK128787 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GALLO, RICHARD L, SALZMAN, NITA H · 2021 to 2024
$2.6MThe skin microbiome in acneR01AR074302 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GALLO, RICHARD L, MODLIN, ROBERT L · 2018 to 2022
$2.6MConflict and Cooperation between AMP Species on the skinR01AR076082 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GALLO, RICHARD L, NAKATSUJI, TERUAKI · 2019 to 2023
$2.3MSkin Defense by Dermal AdipocytesR01AR069653 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GALLO, RICHARD L · 2016 to 2020
$1.9MNCI NIH HHS P30 CA023100NIAID NIH HHS R01 AI022553NIAID NIH HHS R37 AI052453NIAMS NIH HHS P30 AR075043NIAMS NIH HHS P50 AR080594NIAMS NIH HHS R01 AR040312NIAMS NIH HHS R01 AR069653NIAMS NIH HHS R01 AR074302NIAMS NIH HHS R01 AR076082NIDDK NIH HHS R01 DK128787
Abstract
Innate immune defense against deep tissue infection by
Indexed as
Acne VulgarisAnti-Infective AgentsSkin DiseasesAnimalsAnti-Bacterial AgentsHumansMicePropionibacterium acnesStaphylococcus aureusTretinoinAnti-Bacterial AgentsAnti-Infective AgentsTretinoin
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.