Evidence map›Paper›PMID 35171450›Full record

ArticleJournal of molecular neuroscience : MN2022

Associations of ARHGAP26 Polymorphisms with Alzheimer's Disease and Cardiovascular Disease.

Kesheng Wang, Yongke Lu, Deana F Morrow, Danqing Xiao, Chun Xu, Alzheimer’s Disease Neuroimaging Initiative

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Kesheng WangDepartment of Family and Community Health, School of Nursing, Health Sciences Center, West Virginia University, Post Office Box 9600 - Office 6419, Morgantown, WV, 26506, USA. kesheng.wang@hsc.wvu.edu.ORCID http://orcid.org/0000-0001-7118-3877
Yongke LuDepartment of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, 25755, USA.
Deana F MorrowSchool of Social Work, West Virginia University, Morgantown, WV, 26506, USA.
Danqing XiaoDepartment of STEM, School of Arts and Sciences, Regis College, Weston, MA, 02493, USA.
Chun XuDepartment of Health and Biomedical Sciences, College of Health Professions, University of Texas Rio Grande Valley, TX, 78520, Brownsville, USA. chun.xu@utrgv.edu.
Alzheimer’s Disease Neuroimaging Initiative
West Virginia University · USMarshall University · USRegis College · USThe University of Texas Rio Grande Valley · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Rho GTPase activating protein 26 (ARHGAP26) gene has been reported to be associated with neuropsychiatric diseases and neurodegenerative diseases including Parkinson's disease. We examined whether the ARHGAP26 gene is associated with Alzheimer's disease (AD) and/or cardiovascular disease (CVD). Multivariable logistic regression model was used to examine the associations of 154 single nucleotide polymorphisms (SNPs) within the ARHGAP26 gene with AD and CVD using the Alzheimer's Disease Neuroimaging Initiative 1 (ADNI-1) cohort. Fourteen SNPs were associated with AD (top SNP rs3776362 with p = 3.43 × 10

Indexed as

Alzheimer DiseaseCardiovascular DiseasesGTPase-Activating ProteinsGenome-Wide Association StudyHumansARHGAP26 protein, humanGTPase-Activating ProteinsAlzheimer diseaseARHGAP26Cardiovascular diseaseeQTLsRegulomeDBSingle nucleotide polymorphism

Identifiers

PMID35171450
OpenAlexW4213229622

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.