Evidence map›Paper›PMID 35171059›Full record

ArticlePharmaceutical biology2022

Wasp venom from

Hairong Zhao, Mei Wang, Xi Huang, Xiumei Wu, Huai Xiao, Fanmao Jin, Jiaming Lv, Jidong Cheng, Yu Zhao, Chenggui Zhang

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Effects of wasp venom on venous thrombosis in rats.Iranian journal of basic medical sciences · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hairong ZhaoYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, Dali University, Dali, PR China.ORCID 0000-0003-0000-8136
Mei WangYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, Dali University, Dali, PR China.
Xi HuangYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, Dali University, Dali, PR China.
Xiumei WuYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, Dali University, Dali, PR China.
Huai XiaoYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, Dali University, Dali, PR China.
Fanmao JinYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, Dali University, Dali, PR China.
Jiaming LvSchool of Medicine, Xiamen University, Xiamen, PR China.
Jidong ChengSchool of Medicine, Xiamen University, Xiamen, PR China.
Yu ZhaoYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, Dali University, Dali, PR China.
Chenggui ZhangYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, Dali University, Dali, PR China.ORCID 0000-0002-2691-5079
Dali University · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextAcute ischaemic stroke (AIS) is a major cause of disability and death, which is a serious threat to human health and life. Wasp venom extracted from

objectiveThis study investigated the effects of wasp venom on AIS in rats. MATERIAL AND

methodsWe used a transient middle cerebral artery occlusion (MCAO) model in Sprague-Dawley rats (260-280 g,

resultsCompared with the MCAO group, wasp venom (0.6 mg/kg) improved neurological impairment, accelerated CBF recovery (205.6 ± 52.92

conclusionsWasp venom exhibited a potential neuroprotective effect for AIS. In the future, we will focus on determining whether the observed actions were due to a single compound or the interaction of multiple components of the venom.

Indexed as

AnimalsApoptosisBrain IschemiaDose-Response Relationship, DrugInfarction, Middle Cerebral ArteryIschemic StrokeMaleNeuronsNeuroprotective AgentsRatsRats, Sprague-DawleyWaspsWasp VenomsNeuroprotective AgentsWasp Venomsbrain–blood barrierIschaemic strokeneuroinflammation

Identifiers

PMID35171059
PMCPMC8863380
OpenAlexW4213257067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.