Evidence map›Paper›PMID 35171033›Full record

ArticleMicrobiology spectrum2022

Characterization of a Conjugative Multidrug Resistance IncP-2 Megaplasmid, pPAG5, from a Clinical Pseudomonas aeruginosa Isolate.

Meng Li, Congcong Guan, Gaoyu Song, Xiaoxi Gao, Weina Yang, Tietao Wang, Yani Zhang

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Meng LiKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest Universitygrid.412262.1, Xi'an, People's Republic of China.ORCID 0000-0002-2430-9665
Congcong GuanKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest Universitygrid.412262.1, Xi'an, People's Republic of China.
Gaoyu SongKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest Universitygrid.412262.1, Xi'an, People's Republic of China.
Xiaoxi GaoKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest Universitygrid.412262.1, Xi'an, People's Republic of China.
Weina YangDepartment of Clinical Laboratory, The Children's Hospital of Xi'an City, Xi'an, People's Republic of China.
Tietao WangKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest Universitygrid.412262.1, Xi'an, People's Republic of China.
Yani ZhangKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest Universitygrid.412262.1, Xi'an, People's Republic of China.ORCID 0000-0002-8583-3639
Ministry of Education of the People's Republic of China · CNXi’an Children’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spread of resistance genes via horizontal plasmid transfer plays a significant role in the formation of multidrug-resistant (MDR) Pseudomonas aeruginosa strains. Here, we identified a megaplasmid (ca. 513 kb), designated pPAG5, which was recovered from a clinical multidrug-resistant P. aeruginosa PAG5 strain. The pPAG5 plasmid belonged to the IncP-2 incompatibility group. Two large multidrug resistance regions (MDR-1 and MDR-2) and two heavy metal resistance operons (

Indexed as

Anti-Bacterial AgentsBacterial ProteinsConjugation, GeneticDNA HelicasesDrug Resistance, Multiple, BacterialEscherichia coliEvolution, MolecularHumansMicrobial Sensitivity TestsOperonPhylogenyPlasmidsPseudomonas aeruginosaPseudomonas InfectionsTrans-ActivatorsAnti-Bacterial AgentsBacterial ProteinsDNA Helicasesreplication initiator proteinTrans-Activatorsconjugative plasmidIncP-2 plasmidmultidrug resistanceplasmid evolutionPseudomonas aeruginosa

Identifiers

PMID35171033
PMCPMC8849076
OpenAlexW4213036840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.