Evidence map›Paper›PMID 35171021›Full record

ArticleMicrobiology spectrum2022

Effect of Tranexamic Acid against Staphylococcus spp. and Cutibacterium acnes Associated with Peri-Implant Infection: Results from an

Antonio Benjumea, Marta Díaz-Navarro, Rama Hafian, Mar Sánchez-Somolinos, Javier Vaquero, Francisco Chana, Patricia Muñoz, María Guembe

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Effects of Tranexamic Acid in Combination with Teicoplanin AgainstInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Fewer severe infections with tranexamic acid in patients with hematologic malignancies.Research and practice in thrombosis and haemostasis · 2024
    Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Antonio BenjumeaDepartment of Orthopaedic Surgery and Traumatology, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.
Marta Díaz-NavarroDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.
Rama HafianSchool of Biology, Universidad Complutense de Madrid, Madrid, Spain.
Mar Sánchez-SomolinosDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.
Javier VaqueroDepartment of Orthopaedic Surgery and Traumatology, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.
Francisco ChanaDepartment of Orthopaedic Surgery and Traumatology, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.
Patricia MuñozDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.ORCID 0000-0001-5706-5583
María GuembeDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.ORCID 0000-0002-7607-5848
Hospital General Universitario Gregorio Marañón · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tranexamic acid (TXA) is extensively used in orthopedic surgery and traumatology as an antifibrinolytic agent to control intra- and postoperative bleeding and, therefore, indirectly, to reduce postsurgery infection rates. The hypothesis of an additional antibiotic effect against microorganisms associated with periprosthetic joint infection needs to be further evaluated. We aimed to assess whether TXA could reduce bacterial growth using an

Indexed as

Anti-Bacterial AgentsBiofilmsGram-Positive Bacterial InfectionsHumansMicrobial Sensitivity TestsPropionibacteriaceaeProstheses and ImplantsProsthesis-Related InfectionsStaphylococcal InfectionsStaphylococcusTranexamic AcidAnti-Bacterial AgentsTranexamic Acidantimicrobial effectbacterial growthbiofilmin vitro modeltranexamic acid

Identifiers

PMID35171021
PMCPMC8849059
OpenAlexW4213299488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.