Evidence map›Paper›PMID 35170987›Full record

ArticleJournal of the American Heart Association2022

Vertebrobasilar Stroke: Association Between Infarction Patterns and Quantitative Magnetic Resonance Angiography Flow State.

Ahmad A Ballout, Richard B Libman, Julia R Schneider, Karen Black, Panagiotis Sideras, Jason J Wang, Timothy G White, Amir R Dehdashti, Henry H Woo, Jeffrey M Katz

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ahmad A BalloutDepartment of Neurology Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Manhasset NY.ORCID 0000-0001-7408-4233
Richard B LibmanDepartment of Neurology Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Manhasset NY.
Julia R SchneiderDepartment of Neurology Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Manhasset NY.
Karen BlackDepartment of Radiology Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Manhasset NY.ORCID 0000-0001-8063-5222
Panagiotis SiderasDepartment of Radiology Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Manhasset NY.
Jason J WangDepartment of Radiology Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Manhasset NY.ORCID 0000-0002-6211-2572
Timothy G WhiteDepartment of Neurosurgery Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Manhasset NY.ORCID 0000-0002-3604-4334
Amir R DehdashtiDepartment of Neurosurgery Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Manhasset NY.
Henry H WooDepartment of Neurosurgery Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Manhasset NY.
Jeffrey M KatzDepartment of Neurology Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Manhasset NY.ORCID 0000-0002-8193-3683
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell · USHofstra University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Treatment and prognosis of vertebrobasilar atherosclerotic disease differs depending on stroke mechanism, such as artery-to-artery embolism, branch atheromatous disease, and hemodynamic ischemia. Our aim was to investigate the relationship between infarction pattern and flow status using quantitative magnetic resonance angiography (QMRA), to determine the validity of using infarction patterns to infer stroke mechanism. Methods and Results This is a retrospective study of patients with ischemic stroke with intra- or extracranial vertebrobasilar atherosclerotic stenosis, who underwent magnetic resonance imaging of the brain, neurovascular imaging, and QMRA, between 2009 and 2021. Patients with cerebral infarction predating or following QMRA by ≥1 year, or QMRA studies performed for basilar thrombosis, vertebral dissection, or only postangioplasty/stenting, were excluded. Poststenotic flow (basilar and posterior cerebral arteries) was dichotomized as low-flow or normal-flow based on published criteria. Of 1211 consecutive patients who underwent QMRA noninvasive optimal analysis, 69 met inclusion. Mixed patterns were most common (46.4%), followed by perforator (23.2%), borderzone (14.5%), and territorial (15.9%). Patients with low-flow had a significantly higher rate of borderzone+ patterns (borderzone alone or in mixed pattern) compared with patients with normal-flow (77.4% low-flow versus 39.5% normal-flow,

Indexed as

StrokeVertebrobasilar InsufficiencyCerebral InfarctionCerebrovascular CirculationHumansMagnetic Resonance AngiographyRetrospective Studieshemodynamicsposterior circulationvertebrobasilar disease

Identifiers

PMID35170987
PMCPMC9075089
OpenAlexW4213140437

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.