Evidence map›Paper›PMID 35170979›Full record

ArticleJournal of virology2022

Xiaohui Zhao, Huijun Yuan, Hang Yang, Yan Liu, Meng Xun, Xiaozhen Li, Tingting Fan, Bo Wu, Shangrui Guo, Hongliang Wang

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaohui ZhaoDepartment of Pathogen Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Huijun YuanDepartment of Pathogen Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Hang YangDepartment of Pathogen Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yan LiuDepartment of Pathogen Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Meng XunDepartment of Pathogen Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Xiaozhen LiDepartment of Pathogen Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Tingting FanDepartment of Pathogen Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Bo WuDepartment of Pathogen Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Shangrui GuoDepartment of Pathogen Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Hongliang WangDepartment of Pathogen Biology and Immunology, Xi'an Jiaotong University Health Science Center, Xi'an, China.ORCID 0000-0002-3304-2683
Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterovirus 71 (EV71) is deemed a reemergent pathogen, with recent outbreaks worldwide. EV71 infection causes hand, foot, and mouth disease (HFMD) and has been associated with severe cardiac and central nervous system complications and even death. Viruses need host factors to complete their life cycle; therefore, the identification of the host factors for EV71 infection is pivotal to new antiviral research. Emerging evidence has highlighted the importance of protein acetylation during infection by various human viruses. The endoplasmic reticulum (ER), as the prominent organelle of EV71 replication, also has a unique acetylation regulation mechanism. However, the pathogenesis of EV71 and its relationship with the ER-based acetylation machinery are not fully understood. In this study, we demonstrated for the first time that the ER-resident acetyltransferase

Indexed as

AcetyltransferasesEnterovirus A, HumanEnterovirus InfectionsViral Nonstructural ProteinsVirus ReplicationHumansAcetyltransferasesNAT8 protein, humanViral Nonstructural Proteinsacetylationenterovirusviral replication

Identifiers

PMID35170979
PMCPMC8941898
OpenAlexW4213189418

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.