Evidence map›Paper›PMID 35170656›Full record

ArticleArquivos brasileiros de oftalmologia

A novel interlamellar oral mucosa graft surgery technique using fibrin glue for the treatment of trichiasis.

William W Binotti, Ana Carla B de Aguiar, Aline A Barbosa, Sergio V Burnier

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Article in Arquivos brasileiros de oftalmologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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4 authors.

William W BinottiOphthalmology Department, Complexo Hospitalar Ouro Verde "Prefeito Edivaldo Orsi", Campinas, SP, Brazil.ORCID 0000-0001-6761-8807
Ana Carla B de AguiarOphthalmology Department, Complexo Hospitalar Ouro Verde "Prefeito Edivaldo Orsi", Campinas, SP, Brazil.
Aline A BarbosaOphthalmology Department, Complexo Hospitalar Ouro Verde "Prefeito Edivaldo Orsi", Campinas, SP, Brazil.
Sergio V BurnierOphthalmology Department, Complexo Hospitalar Ouro Verde "Prefeito Edivaldo Orsi", Campinas, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to evaluate the long-term outcomes of patients with trichiasis treated with a modified interlamellar oral mucosa graft surgery technique using fibrin glue.

methodsA prospective study was conducted at the Oculoplastic Department of Ouro Verde Hospital Complex. Patients with recurrent trichiasis without entropion who did not respond to conventional therapy, underwent intermarginal lamellar splitting of the eyelid and oral mucous graft insertion with fibrin glue replacing sutures. They were then evaluated at 1-day, 1-week, 1-month, 6-month, and 4-year follow-ups. Graft adherence, symptom resolution, esthetic satisfaction, overall patient satisfaction, and trichiasis recurrence were assessed at 6-month and 4-year follow-ups.

resultsFifteen patients (a total of 19 eyes) were included, of whom 10 (66.7%) were female and 5 (33.3%) were male. The mean age was 75.4 ± 10.5 years (range, 54-98 years). Acquired trichiasis was the main cause. Of the patients with acquired trichiasis, 12 (86.7%) had chronic blepharitis, 2 (13.3%) had an undetermined cause, and one (6.7%) had trachomatous trichiasis. Most cases involved only one eyelid segment (89.4%) and =5 lashes (84.2%; minor trichiasis). No adverse reactions from the fibrin glue were reported and no sutures were required after graft placement. At 6 months, no graft failures occurred, 17 eyes of 13 patients (89.4%) showed good graft adherence, 2 eyes of 2 patients (10.5%) showed partial graft adherence, and 2 eyes of 1 patient (10.5%) had trichiasis recurrence. At 4-year follow-up, no graft failure occurred, 3 patients (3 eyes) were lost to follow-up, and 2 eyes of 2 patients (14.2%) had trichiasis recurrence. The 4-year cumulative success rate was 78.9%.

conclusionsThe modified interlamellar surgery with fibrin glue showed a good long-term success rate. This technique reduces surgical time, facilitates smaller graft insertion, and therefore, should be considered for recalcitrant minor trichiasis without entropion.>.

Indexed as

Fibrin Tissue AdhesiveMouth MucosaAgedAged, 80 and overFemaleHumansMaleMiddle AgedProspective StudiesFibrin Tissue Adhesive

Identifiers

PMID35170656
PMCPMC11826660

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.