Evidence map›Paper›PMID 35170417›Full record

ArticleCurrent hypertension reviews2022

Hormone-Dependent Regulation of Renin and Effects on Prorenin Receptor Signaling in the Collecting Duct.

Lucienne S Lara, Alexis A Gonzalez, Matthew T Hennrikus, Minolfa C Prieto

Open access · greenAbstract read
In one paragraph

Article in Current hypertension reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Biomolecules · 2026
    Article
  2. Article
  3. Review
  4. Calcium signalling and transport in the kidney.Nature reviews. Nephrology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Lucienne S LaraInstituto de Ciencias Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Alexis A GonzalezInstituto de Química, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.
Matthew T HennrikusDepartment of Physiology, Tulane University School of Medicine, New Orleans, LA, USA.
Minolfa C PrietoDepartment of Physiology, Tulane University School of Medicine, New Orleans, LA, USA.
Tulane University · USPontificia Universidad Católica de Valparaíso · CLUniversidade Federal do Rio de Janeiro · BR

Funding

UAB Center for Clinical and Translational Science (CCTS)UL1TR001417 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2015 to 2018
$31.4M
TULANE COBRE: TRANSGENIC &GENE-TARGETED ANIMAL COREP20RR017659 · NCRR · TULANE UNIVERSITY OF LOUISIANA · PI NAVAR, LUIS GABRIEL · 2002 to 2011
$22.1M
PLEIOTROPIC EFFECTS OF PRORENIN RECEPOR IN COLLECTING DUCT AND INTRARENAL RAS ACTIVATIONR01DK104375 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI PRIETO, MINOLFA C · 2014 to 2018
$1.7M
NCATS NIH HHS UL1 TR001417NCRR NIH HHS P20 RR017659NIDDK NIH HHS R01 DK104375
6 · The paper itself

Abstract

The production of renin by the principal cells of the collecting duct has widened our understanding of the regulation of intrarenal angiotensin II (Ang II) generation and blood pressure. In the collecting duct, Ang II increases the synthesis and secretion of renin by mechanisms involving the activation of Ang II type 1 receptor (AT1R) via stimulation of the PKCα, Ca

Indexed as

HypertensionReninAngiotensin IIBlood PressureHumansProrenin ReceptorReceptors, Cell SurfaceRenin-Angiotensin SystemAngiotensin IIATP6AP2 protein, humanProrenin ReceptorReceptors, Cell SurfaceReninbradykininintrarenal angiotensin IInitric oxideprostaglandinsprotein kinasevasopressin

Identifiers

PMID35170417
PMCPMC10132771
OpenAlexW4213040369

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.