Evidence map›Paper›PMID 35170400›Full record

ArticleBioengineered2022

Hepatoprotective mechanism of

Guoyan Jiang, Chunhong Sun, Xiaodong Wang, Jie Mei, Chen Li, Honghong Zhan, Yixuan Liao, Yongjun Zhu, Jingxin Mao

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Effect of Probiotics Therapy on Nonalcoholic Fatty Liver Disease.Computational and mathematical methods in medicine · 2022
    Pooled it
  5. Evaluation of the Effect ofInternational journal of clinical practice · 2024
    Trial
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  9. Evaluating the toxicity and efficacy of the endophytic bacteriumBiochemistry and biophysics reports · 2025
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  10. Polyherbal Therapeutics Mitigate CClReproductive sciences (Thousand Oaks, Calif.) · 2025
    Article
  11. Network analysis of antimicrobial resistance inNAR genomics and bioinformatics · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Liver disorders and phytotherapy.Toxicology reports · 2025
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Guoyan JiangDepartment of Emergency, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chunhong SunDepartment of Emergency, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiaodong WangChongqing Medical and Pharmaceutical College, School of Clinical medicine, Chongqing, China.
Jie MeiDepartment of periodontal, Stomatological Hospital of Chongqing Medical University, Chongqing, China.
Chen LiDepartment of Biology, Chemistry, Pharmacy, Free University of Berlin, Berlin, Germany.
Honghong ZhanCollege of Pharmaceutical Sciences, Southwest University, Chongqing, China.
Yixuan LiaoCollege of Pharmaceutical Sciences, Southwest University, Chongqing, China.
Yongjun ZhuDepartment of Orthopedics, The Ninth People's Hospital of Chongqing, Chongqing, China.
Jingxin MaoChongqing Medical and Pharmaceutical College, School of Clinical medicine, Chongqing, China.ORCID 0000-0002-2813-1702
Southwest University · CNChongqing Medical University · CNFreie Universität Berlin · DESchool of Clinical Research · USStomatological Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study aimed to identify the key active components in

Indexed as

Drugs, Chinese HerbalNon-alcoholic Fatty Liver DiseaseSilymarinAntioxidantsHumansMolecular Docking SimulationNetwork PharmacologySilybum marianumAntioxidantsDrugs, Chinese HerbalSilymarinhepatoprotective mechanismNAFLDnetwork pharmacologyNonalcoholic fatty liver diseaseSilybum marianumsilymarin

Identifiers

PMID35170400
PMCPMC8974060
OpenAlexW4213255494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.