Evidence map›Paper›PMID 35170083›Full record

ArticleJournal of veterinary internal medicine2022

Ultrasonographic patterns, clinical findings, and prognostic variables in dogs from Asia with gallbladder mucocele.

Jared A Jaffey, Rachael Kreisler, Kate Shumway, Yan-Jane Lee, Chung-Hui Lin, Lawren L Durocher-Babek, Kyoung-Won Seo, Hojung Choi, Ko Nakashima, Hiromi Harada and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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  5. Acquired dysfunction of CFTR underlies cystic fibrosis-like disease of the canine gallbladder.American journal of physiology. Gastrointestinal and liver physiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 5 countries.

Jared A JaffeyDepartment of Specialty Medicine, Midwestern University College of Veterinary Medicine, Glendale, Arizona, USA.ORCID https://orcid.org/0000-0002-0270-4728
Rachael KreislerDepartment of Pathology and Population Medicine, Midwestern University College of Veterinary Medicine, Glendale, Arizona, USA.
Kate ShumwayDepartment of Veterinary Medicine and Surgery, Veterinary Health Center, University of Missouri, Columbia, Missouri, USA.
Yan-Jane LeeGraduate Institute of Veterinary Clinical Sciences, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.ORCID https://orcid.org/0000-0003-4884-7019
Chung-Hui LinGraduate Institute of Veterinary Clinical Sciences, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.ORCID https://orcid.org/0000-0002-5276-3179
Lawren L Durocher-BabekVeterinary Specialty Hospital, Wan Chai, Hong Kong.
Kyoung-Won SeoDepartment of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University, Daejeon, South Korea.
Hojung ChoiDepartment of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University, Daejeon, South Korea.
Ko NakashimaJapan Small Animal Medical Center, Saitama, Japan.ORCID https://orcid.org/0000-0002-4823-4821
Hiromi HaradaJapan Small Animal Medical Center, Saitama, Japan.
Hideyuki KanemotoDVMs Animal Medical Center, Yokohama, Japan.
Lee-Shuan LinDepartment of Veterinary Medicine, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung, Taiwan.
Japan Small Animal Medical Center · JPMidwestern University · USNational Taiwan University · TWChungnam National University · KRMissouri College · USNational Pingtung University of Science and Technology · TWOrthopedic Specialty Hospital · USSeoul National University · KRThe Schwarzman Animal Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGallbladder mucocele (GBM) is a common biliary disorder in dogs that can be categorized into 6 types, but the value of this classification scheme remains unknown. Cholecystectomy is associated with high death rates and warrants additional interrogation.

objectivesInvestigate the clinical value of ultrasonographic diagnosis of type of GBM and identify prognostic factors in dogs with GBM undergoing cholecystectomy. ANIMALS: Two hundred sixteen dogs.

methodsRetrospective cohort study. Dogs with GBM diagnosed from 2014 to 2019 at 6 veterinary referral hospitals in Asia. Ultrasonogram images were reviewed and a GBM type (ie, types I-VI) assigned.

resultsDogs with GBM type V as compared to I (OR, 8.6; 95% CI, 2.6-27.8; P < .001) and III (OR, 10.0; 95% CI, 2.5-40.8; P = .001), and dogs with type VI compared to I (OR, 10.5; 95% CI, 1.8-61.2; P = .009) and III (OR, 12.3; 95% CI, 1.8-83.9; P = .01) were more likely to exhibit signs of biliary tract disease. Independent predictors of death after cholecystectomy included age (OR, 2.81; 95% CI, 1.41-5.59; P = .003) and intraoperative systolic blood pressure (SBP) nadir. There was an interaction between SBP nadir and gallbladder rupture; SBP nadir in dogs with (OR, 0.92; 95% CI, 0.89-0.94; P < .001) and without (OR, 0.88; 95% CI, 0.82-0.93; P < .001) gallbladder rupture. CONCLUSION AND CLINICAL IMPORTANCE: Increasing developmental stage of GBM could be associated with an increased likelihood of biliary tract related clinical signs. Nadir SBP deserves further investigation as a prognostic or potentially modifiable variable, particularly in the presence of gallbladder rupture.

Indexed as

Dog DiseasesGallbladder DiseasesMucoceleAnimalsDogsGallbladderHumansPrognosisRetrospective Studiesbiliaryblood pressurecaninecholecystectomyhypotensionsurvival

Identifiers

PMID35170083
PMCPMC8965224
OpenAlexW4212962375

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.