ArticleThe New phytologist2022
Tomato CRABS CLAW paralogues interact with chromatin remodelling factors to mediate carpel development and floral determinacy.
Article in The New phytologist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- The Phylogeny of Brassicaceae YABBYs and theInternational journal of molecular sciences · 2026Article
- Molecular Regulatory Mechanism of Inflorescence, Flower and Fruit Development in Tomato.Plants (Basel, Switzerland) · 2026Review
- Integrated Analysis of Transcriptomes and Pectinase Gene Families Reveals a Novel Pathway Mediating Tomato Fruit Malformation.International journal of molecular sciences · 2025Article
- The Role of CRABS CLAW Transcription Factor in Floral Organ Development in Plants.International journal of molecular sciences · 2025Review
- Editing multiple genes in Physalis pubescens provides valuable lessons and implications for creating new germplasm and varieties of Physalis crops.Plant & cell physiology · 2025Article
- Comparative Transcriptome Reveals Conserved Gene Expression in Reproductive Organs in Solanaceae.International journal of molecular sciences · 2025Article
- Solanaceae pan-genomes reveal extensive fractionation and functional innovation of duplicated genes.Plant communications · 2025Article
- SlKNUCKLES regulates floral meristem activity and controls fruit size inHorticulture research · 2025Article
- Morphological and molecular mechanisms of floral nectary development in Chinese Jujube.BMC plant biology · 2024Article
- Review
- JOINTLESS Maintains Inflorescence Meristem Identity in Tomato.Plant & cell physiology · 2024Article
- SlCRCa is a key D-class gene controlling ovule fate determination in tomato.Plant biotechnology journal · 2024Article
- The YABBY Transcription Factor, SlYABBY2a, Positively Regulates Fruit Septum Development and Ripening in Tomatoes.International journal of molecular sciences · 2024Article
- Heat stress impairs floral meristem termination and fruit development by affecting the BR-SlCRCa cascade in tomato.Plant communications · 2024Article
- Candidate Gene Identification and Transcriptome Analysis of TomatoInternational journal of molecular sciences · 2024Article
- Insights into the functional role of tomatoHorticulture research · 2024Article
- New Advances in the Study of Regulation of Tomato Flowering-Related Genes Using Biotechnological Approaches.Plants (Basel, Switzerland) · 2024Review
- Molecular and genetic regulations of fleshy fruit shape and lessons fromHorticulture research · 2023Article
- BELL1 interacts with CRABS CLAW and INNER NO OUTER to regulate ovule and seed development in pomegranate.Plant physiology · 2023Article
- Applications of CRISPR/Cas genome editing in economically important fruit crops: recent advances and future directions.Molecular horticulture · 2023Review
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CRABS CLAW (CRC) orthologues play a crucial role in floral meristem (FM) determinacy and gynoecium formation across angiosperms, the key developmental processes for ensuring successful plant reproduction and crop production. However, the mechanisms behind CRC mediated FM termination are far from fully understood. Here, we addressed the functional characterization of tomato (Solanum lycopersicum) paralogous CRC genes. Using mapping-by-sequencing, RNA interference and CRISPR/Cas9 techniques, expression analyses, protein-protein interaction assays and Arabidopsis complementation experiments, we examined their potential roles in FM determinacy and carpel formation. We revealed that the incomplete penetrance and variable expressivity of the indeterminate carpel-inside-carpel phenotype observed in fruit iterative growth (fig) mutant plants are due to the lack of function of the S. lycopersicum CRC homologue SlCRCa. Furthermore, a detailed functional analysis of tomato CRC paralogues, SlCRCa and SlCRCb, allowed us to propose that they operate as positive regulators of FM determinacy by acting in a compensatory and partially redundant manner to safeguard the proper formation of flowers and fruits. Our results uncover for the first time the physical interaction of putative CRC orthologues with members of the chromatin remodelling complex that epigenetically represses WUSCHEL expression through histone deacetylation to ensure the proper termination of floral stem cell activity.
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