Evidence map›Paper›PMID 35169942›Full record

ArticleInternal and emergency medicine2022

Radiographic assessment of lung edema (RALE) score is associated with clinical outcomes in patients with refractory cardiogenic shock and refractory cardiac arrest after percutaneous implantation of extracorporeal life support.

Ingo Voigt, Marco Mighali, Daniela Manda, Phillip Aurich, Oliver Bruder

Abstract read
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In one paragraph

Article in Internal and emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Observational
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  4. Article
  5. Article
  6. Article
  7. Automatic Quantification of COVID-19 Pulmonary Edema by Self-supervised Contrastive Learning.Medical image learning with limited and noisy data : second international workshop, MILLanD 2023, held in conjunction with MICCAI 2023, Vancouver, BC, Canada, October 8, 2023, proceedings. MILLanD (Workshop) : (2nd : 2023 : Vancouver, B... · 2023
    Article
  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ingo VoigtDepartment of Acute and Emergency Medicine, Elisabeth-Hospital Essen, Essen, Germany. i.voigt@contilia.de.ORCID http://orcid.org/0000-0001-6820-3005
Marco MighaliDepartment of Acute and Emergency Medicine, Elisabeth-Hospital Essen, Essen, Germany.
Daniela MandaDepartment of Acute and Emergency Medicine, Elisabeth-Hospital Essen, Essen, Germany.
Phillip AurichDepartment of Acute and Emergency Medicine, Elisabeth-Hospital Essen, Essen, Germany.
Oliver BruderDepartment of Cardiology and Angiology, Elisabeth-Hospital Essen, Essen, Germany.
Elisabeth-Krankenhaus Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

VA-ECMO is a promising therapeutic option in refractory cardiogenic shock (RCS) and refractory cardiac arrest (RCA). However, increase in left ventricular afterload enhances further reduction of LV contractility and pulmonary edema. The aim of this study was to evaluate pulmonary edema based on the RALE score and the prognostic value of the score on ECLS weaning and mortality. In this retrospective study, data from 40 patients (16 RCAs and 24 RCSs) were analyzed. Demographic, clinical data and the RALE score for evaluating pulmonary edema were assessed. Descriptive statistics, intraclass correlation, and receiver operating characteristic (ROC) curves were computed. Weaning from ECLS was successful in 30 (75%) patients, 16 patients (40%) were discharged alive. Overall, the survivors were younger, presenting with a higher left ventricular ejection fraction (30 ± 2% vs.23 ± 9%;p < 0.01) and a lower initial serum lactate concentration 7.7 ± 4.5 mmol/l vs. 11.5 ± 4.9 mmol/l; p = 0.017). Survivors had lower RALE scores than non-survivors (16.3 ± 9.4 vs. 26.4 ± 10.4; p = 0.0034). The interobserver variability of the RALE score was good (0.832). The AUC predicting mortality and weaning from ECLS presented comparable results to the established parameters (SAVE, serum lactate). Implementation of the RALE score could support prediction of outcome parameters during VA-ECMO therapy.

Indexed as

Extracorporeal Membrane OxygenationHeart ArrestPulmonary EdemaEdemaHumansLactatesLungRespiratory SoundsRetrospective StudiesShock, CardiogenicStroke VolumeVentricular Function, LeftLactatesCardiac arrestCardiogenic shockChest X-rayPrognosisPulmonary edemaVA-ECMO

Identifiers

PMID35169942
OpenAlexW4213123209

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.