Evidence map›Paper›PMID 35169902›Full record

ArticleInternational journal of legal medicine2022

A unique case of death by MDPHP with no other co-ingestion: a forensic toxicology case.

Domenico Di Candia, Michele Boracchi, Barbara Ciprandi, Gaia Giordano, Riccardo Zoja

Open access · hybridAbstract readCase Reports
In one paragraph

Article in International journal of legal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Domenico Di CandiaDipartimento Di Scienze Biomediche Per La Salute-Sezione Di Medicina Legale E Delle Assicurazioni, Università Degli Studi Di Milano, via Luigi Mangiagalli, 37, 20133, Milan, Italy.ORCID http://orcid.org/0000-0003-1401-6815
Michele BoracchiDipartimento Di Scienze Biomediche Per La Salute-Sezione Di Medicina Legale E Delle Assicurazioni, Università Degli Studi Di Milano, via Luigi Mangiagalli, 37, 20133, Milan, Italy. mboracchi@hotmail.com.ORCID http://orcid.org/0000-0002-4240-4121
Barbara CiprandiDipartimento Di Scienze Biomediche Per La Salute-Sezione Di Medicina Legale E Delle Assicurazioni, Università Degli Studi Di Milano, via Luigi Mangiagalli, 37, 20133, Milan, Italy.
Gaia GiordanoDipartimento Di Scienze Biomediche Per La Salute-Sezione Di Medicina Legale E Delle Assicurazioni, Università Degli Studi Di Milano, via Luigi Mangiagalli, 37, 20133, Milan, Italy.ORCID http://orcid.org/0000-0002-6081-0596
Riccardo ZojaDipartimento Di Scienze Biomediche Per La Salute-Sezione Di Medicina Legale E Delle Assicurazioni, Università Degli Studi Di Milano, via Luigi Mangiagalli, 37, 20133, Milan, Italy.ORCID http://orcid.org/0000-0003-3347-2541
University of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic cathinones are a class of psychoactive drugs that have become, in recent years, of quite common observation in medical and toxicological forensic field. MDPHP (3,4-methylenedioxy-α-pyrrolidinohexanophenone) belongs to this class of substances but lethal acute intoxication caused by this specific substance without other co-ingestions has never been described in literature. We are presenting the unique case of a fatal acute intoxication caused by MDPHP in a 48-year-old man carried to the A&E department of a big Milanese hospital where he suddenly deceased after brief time. Clinical records, autopsy examination, histological findings, and toxicological analysis, assessed via a Q-Exactive Orbitrap with a HPLC system and LC/MS-MS system, are discussed. This case report may represent the first case of this type of intoxication and might help in improving recognition and treatment of these particular cases.

Indexed as

EatingPsychotropic DrugsAutopsyChromatography, LiquidForensic ToxicologyHumansMaleMiddle AgedPsychotropic DrugsAutopsyLethal intoxicationMDPHPSynthetic cathinones

Identifiers

PMID35169902
PMCPMC9375735
OpenAlexW4213274159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.