Evidence map›Paper›PMID 35169878›Full record

ArticleSurgical endoscopy2022

Impedance planimetry (EndoFLIP™) after magnetic sphincter augmentation (LINX®) compared to fundoplication.

Hoover Wu, Mikhail Attaar, Harry J Wong, Michelle Campbell, Kristine Kuchta, Woody Denham, John Linn, Michael B Ujiki

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05807763 (Selective Use of Fundoplication in Laparoscopic Paraesophageal Hernia Repair Based on Intra-operative Impedance Planimetry), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05807763 naenrolling by invitationnot on this mapstarted 2023, after this paper: background citation

Selective Use of Fundoplication in Laparoscopic Paraesophageal Hernia Repair Based on Intra-operative Impedance Planimetry (FLIP)

TypeinterventionalSponsorThe Foundation for Surgical Innovation and EducationRan2023 to 2029Enrolled260ConditionsParaesophageal HerniaArmsLaparoscopic paraesophageal hernia repair without fundoplication
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hoover WuDepartment of Surgery, NorthShore University Health System, Evanston, IL, USA. hoover.wu@uchospitals.edu.ORCID http://orcid.org/0000-0003-0153-7566
Mikhail AttaarDepartment of Surgery, NorthShore University Health System, Evanston, IL, USA.
Harry J WongDepartment of Surgery, NorthShore University Health System, Evanston, IL, USA.
Michelle CampbellDepartment of Surgery, NorthShore University Health System, Evanston, IL, USA.
Kristine KuchtaNorthShore University Research Institute, Evanston, IL, USA.
Woody DenhamDepartment of Surgery, NorthShore University Health System, Evanston, IL, USA.
John LinnDepartment of Surgery, NorthShore University Health System, Evanston, IL, USA.
Michael B UjikiDepartment of Surgery, NorthShore University Health System, Evanston, IL, USA.
NorthShore University HealthSystem · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFunctional luminal imaging probe (FLIP) use during laparoscopic fundoplication (LF) for gastroesophageal reflux disease is well described. However, there is a lack of data on FLIP measurements during magnetic sphincter augmentation (MSA). This study aims to report our institutional experience in performing FLIP during MSA and to compare these measurements to those obtained during Nissen and Toupet fundoplication. METHODS AND PROCEDURES: A retrospective review of a prospectively maintained quality database was performed. Patients who underwent MSA or LF and had FLIP measurements between April 2018 and June 2021 were included. FLIP measurements at the gastroesophageal junction (GEJ) were recorded without pneumoperitoneum at 40 mL balloon fill after hernia reduction, cruroplasty, and MSA or fundoplication. Reflux symptom index (RSI), GERD-HRQL, and dysphagia score were collected up to 2 years. Group comparisons were made using two-tailed Wilcoxon rank-sum and χ

resultsTwenty-seven patients underwent MSA and 100 patients underwent LF (66% Toupet, 34% Nissen). Type III hiatal hernia was present in 3.7% of MSA patients versus over 50% for fundoplication patients. Minimum diameter, cross-sectional area, and distensibility index (DI) were lower after MSA device placement compared to Nissen or Toupet fundoplication (p < 0.05). Postoperative follow-up showed no differences in RSI, GERD-HRQL, and dysphagia score between MSA and Nissen fundoplication (p > 0.05).

conclusionIntraoperative impedance planimetry provided objective information regarding the geometry of the GEJ during MSA. The ring of magnetic beads restores the anti-reflux barrier and transiently opens with food bolus and belching. The magnetic force of the beads may explain why the DI after MSA is lower yet postoperative quality of life is no different than Nissen fundoplication.

Indexed as

Deglutition DisordersGastroesophageal RefluxLaparoscopyElectric ImpedanceEsophageal Sphincter, LowerFundoplicationHumansQuality of LifeTreatment OutcomeEndoFLIPGERDImpedance planimetryLINXNissenToupet

Identifiers

PMID35169878
OpenAlexW4213258947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.