ReviewBrain communications2022
Persistent neuropsychiatric symptoms after COVID-19: a systematic review and meta-analysis.
Review in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06940609 (Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulation), which is not on this map. Cited by 142 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulation (MANIFEST)
Who cites it
142 citing papers in PubMed, 10 syntheses or guidelines pooled it, 281 citations in OpenAlex.
- Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients.BMC neurology · 2025Pooled it
- Cognitive functions in COVID-19 survivors, approaches strategies, and impact on health systems: a qualitative systematic review.European archives of psychiatry and clinical neuroscience · 2025Pooled it
- Pooled it
- Cognitive domains affected post-COVID-19; a systematic review and meta-analysis.European journal of neurology · 2025Pooled it
- Pooled it
- Neurological and neuropsychiatric manifestations of post-COVID-19 condition in South America: a systematic review of the literature.Arquivos de neuro-psiquiatria · 2024Pooled it
- The use of acupuncture for addressing neurological and neuropsychiatric symptoms in patients with long COVID: a systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- Pooled it
- Attention and memory after COVID-19 as measured by neuropsychological tests: Systematic review and meta-analysis.Acta psychologica · 2023Pooled it
- Prevalence and incidence of neuropsychiatric disorders in post hospitalized COVID-19 patients in South America: a systematic review and meta-analysis.Frontiers in psychiatry · 2023Pooled it
- Remote ischemic conditioning improves neuropsychiatric symptoms in COVID-19 patients: a randomized clinical trial.Frontiers in psychiatry · 2025Trial
- Direct and indirect associations linking COVID-19 severity to internalizing disorders and symptoms among participants in New Haven, CT.Journal of affective disorders · 2026Article
- Post-COVID neuropsychiatric symptoms in India: Prevalence, risk factors, and persistence.Indian journal of psychiatry · 2026Article
- Acute SARS-CoV-2 infection and self-reported post-acute cognitive dysfunctions from the Danish EFTER-COVID survey.Communications medicine · 2026Article
- Prospective associations between Long COVID and mental health: evidence from a population-based study with a nearly three-year follow-up.BMC public health · 2026Article
- Cognitive impairment, depression, and fatigue in post-COVID and post-vaccination syndrome: a large-scale cross-sectional study.European archives of psychiatry and clinical neuroscience · 2026Article
- Detecting Malingered COVID-19 Symptoms Using the Verifiability Approach.Brain and behavior · 2026Article
- Toward characterizing brain fog in long COVID: correlates and impact on measurement metrics.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Association between COVID-19 diagnosis and severe mental health symptoms in adolescents in southern Brazil.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2026Article
- Lingering echoes of SARS-CoV-2: mechanistic insights and management of long COVID syndrome.Inflammopharmacology · 2026Review
82 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 18 institutions in 4 countries.
Funding
Abstract
The nature and extent of persistent neuropsychiatric symptoms after COVID-19 are not established. To help inform mental health service planning in the pandemic recovery phase, we systematically determined the prevalence of neuropsychiatric symptoms in survivors of COVID-19. For this pre-registered systematic review and meta-analysis (PROSPERO ID CRD42021239750), we searched MEDLINE, EMBASE, CINAHL and PsycINFO to 20 February 2021, plus our own curated database. We included peer-reviewed studies reporting neuropsychiatric symptoms at post-acute or later time-points after COVID-19 infection and in control groups where available. For each study, a minimum of two authors extracted summary data. For each symptom, we calculated a pooled prevalence using generalized linear mixed models. Heterogeneity was measured with
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.