ArticleInternational journal of cardiology. Heart & vasculature2022
Echocardiographic predictors of ventricular arrhythmias in patients with non-ischemic cardiomyopathy.
Article in International journal of cardiology. Heart & vasculature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Echocardiographic Markers of Prognosis in Patients Undergoing Ventricular Arrhythmia Ablation.Echocardiography (Mount Kisco, N.Y.) · 2025Article
- Proarrhythmogenic Echocardiographic Markers in Metabolic Syndrome: A Cross-Sectional Study.Life (Basel, Switzerland) · 2025Article
- Strain Imaging and Ventricular Arrhythmia.Diagnostics (Basel, Switzerland) · 2023Review
- Limitations and Future Directions for Risk Assessment of Ventricular Arrhythmia in Acute Myocardial Infarction [Letter].Clinical interventions in aging · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveVentricular arrhythmias (VA) portend a poor prognosis in non-ischemic cardiomyopathy (NICM). In this meta-analysis we evaluated if left ventricular (LV) global longitudinal strain (GLS) and LV mechanical dispersion (LVMD) are associated with VA, specifically in NICM patients.
methodsA systematic review and meta-analysis was performed to determine the predictive value of LV GLS and LVMD for VA in NICM patients. VA endpoints were a composite of sudden cardiac death, VA events (including ventricular tachycardia or ventricular fibrillation), cardiac arrest and appropriate implantable cardioverter-defibrillator (ICD) therapy. Hazard or odds ratios for univariate models were extracted for the relationship between LV GLS and LVMD with VA endpoints.
resultsA total of 984 patients from 6 published studies were included; 231 patients (23.5%) experienced the composite endpoint. NICM patients who experienced VA endpoints had LV GLS impairment compared to those without (weighted mean difference -1.93%; 95% confidence interval (CI) -2.77 to -1.10; p < 0.001) and LV GLS was related to VA endpoints (hazard ratio: 1.12, 95% CI 1.07-1.17, p < 0.001; odds ratio: 1.22, 95% CI 1.08-1.38, p = 0.002). Four studies reported mean LVMD (weighted mean -10.05 ms; 95% CI -28.25 to 8.14; p = 0.28), with 3 reporting risk ratios (1 reported odds ratio and 2 hazard ratios). Only odds ratio demonstrated statistical significance (hazard ratio: 0.47, 95% CI 0.01-22.25, p = 0.70; odds ratio: 1.59, 95% CI 1.14-2.22, p = 0.007).
conclusionLV GLS impairment demonstrates value for predicting VA endpoints in NICM patients. Inclusion of LV GLS may be appropriate in the surveillance, screening, and clinical management of NICM patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.