Evidence map›Paper›PMID 35169545›Full record

ArticleToxicology reports2022

Characteristics of a novel photoinitiator aceanthrenequinone-initiated polymerization and cytocompatibility of its triggered polymer.

Yongjia Xiong, Hailing Zou, Shuhui Wang, Jiawen Guo, Boning Zeng, Pu Xiao, Jing Liu, Feiyue Xing

Erratum issuedAbstract read
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In one paragraph

Article in Toxicology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Yongjia XiongInstitute of Tissue Transplantation and Immunology, Department of Immunobiology, MOE Key Laboratory of Tumor Molecular Biology, Jinan University, Guangzhou, 510632, China.
Hailing ZouInstitute of Tissue Transplantation and Immunology, Department of Immunobiology, MOE Key Laboratory of Tumor Molecular Biology, Jinan University, Guangzhou, 510632, China.
Shuhui WangInstitute of Tissue Transplantation and Immunology, Department of Immunobiology, MOE Key Laboratory of Tumor Molecular Biology, Jinan University, Guangzhou, 510632, China.
Jiawen GuoGuanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, 510055, China.
Boning ZengInstitute of Tissue Transplantation and Immunology, Department of Immunobiology, MOE Key Laboratory of Tumor Molecular Biology, Jinan University, Guangzhou, 510632, China.
Pu XiaoInstitute of Tissue Transplantation and Immunology, Department of Immunobiology, MOE Key Laboratory of Tumor Molecular Biology, Jinan University, Guangzhou, 510632, China.
Jing LiuSchool of Stomatology, Jinan University, Guangzhou, 510632, China.
Feiyue XingInstitute of Tissue Transplantation and Immunology, Department of Immunobiology, MOE Key Laboratory of Tumor Molecular Biology, Jinan University, Guangzhou, 510632, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A number of photoinitiators are available in chemical industry, but less of them in biomedicine or clinical therapy due to the limitation of their cytotoxicity and biocompatibility. Thus, it is urgently necessary to find non-toxic or low-toxic photoinitiators to meet clinical demands. Aceanthrenequinone (AATQ) is a novel photosensitizer with high-photoinitiating ability, but no reports contribute, to date, to its cytotoxicity and biocompatibility. Here, primary cells and various cell lines were exposed to different concentrations of AATQ with or without irradiation. AATQ had the similar photoinitiating conversion efficiency to the extensively used bis(2,4,6-trimethylbenzoyl)-phenylphosphine oxide (BAPO) and higher one than 9,10-phenanthrenequinone (PANQ) with the similar extent of polymerization in depth within a certain range, but displayed much lower cytotoxicity than BAPO under non-irradiation or irradiation. The biocompatibility of BisGMA/TEGDMA polymer prepared by AATQ was superior to that of PANQ, but inferior to that of camphorquinone (CQ) although the far lower dose of AATQ is enough to initiate polymerization of monomer than that of CQ. Hence, AATQ offers a valuable alternative in applications of industrial or biomedical areas.

Indexed as

9,10-phenanthrenequinoneAceanthrenequinoneBiocompatibilityCytotoxicityPhotopolymerization

Identifiers

PMID35169545
PMCPMC8829579

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