Evidence map›Paper›PMID 35169279›Full record

SynthesisHypertension research : official journal of the Japanese Society of Hypertension2022

Association of uterine fibroids with increased blood pressure: a cross-sectional study and meta-analysis.

Yequn Chen, Nianling Xiong, Jiaxin Xiao, Xiru Huang, Rongbing Chen, Shu Ye, Xuerui Tan

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Hypertension research : official journal of the Japanese Society of Hypertension, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Prevalence and associated risk factors of uterine fibroids in the Kingdom of Eswatini.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Uterine fibroids show evidence of shared genetic architecture with blood pressure traits.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yequn Chen *The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Nianling Xiong *Nanchang University Second Affiliated Hospital, Nanchang, Jiangxi, China.
Jiaxin Xiao *The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Xiru HuangThe First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Rongbing ChenThe First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Shu YeThe First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China. sy127@leicester.au.uk.
Xuerui TanThe First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China. doctortxr@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uterine fibroids (UFs) are the most common benign gynecological tumor and greatly affect reproductive health in women of reproductive age. Some studies have indicated an association between UFs and several cardiovascular disease (CVD) risk factors. To determine whether UFs are associated with increased blood pressure, we performed a cross-sectional study and meta-analysis. In the cross-sectional study, 8401 participants who underwent a physical examination at the First Affiliated Hospital of Shantou University Medical College from June 2011 to June 2013 were divided into a uterine fibroid group (1617 cases) and a control group (6784 cases) to assess the relationship between UFs and blood pressure. Then, we conducted a systematic review to confirm the results. The cross-sectional study showed that UFs were associated with an increased rate of elevated blood pressure [OR = 1.35, 95% confidence interval (CI): 1.016-1.792]. The meta-analysis revealed a significant association between UFs and the prevalence of hypertension [pooled OR = 1.44, 95% CI: 1.17-1.75, P = 0.0004; I

Indexed as

HypertensionLeiomyomaUterine NeoplasmsBlood PressureCross-Sectional StudiesFemaleHumansBlood pressure;Hypertension;Uterine fibroids

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.