Evidence map›Paper›PMID 35168984›Full record

ArticleBMJ open2022

Hospital bed occupancy rate is an independent risk factor for COVID-19 inpatient mortality: a pandemic epicentre cohort study.

Francesco Castagna, Xiaonan Xue, Omar Saeed, Rachna Kataria, Yoram A Puius, Snehal R Patel, Mario J Garcia, Andrew D Racine, Daniel B Sims, Ulrich P Jorde

Abstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francesco CastagnaAlbert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0002-8983-4866
Xiaonan XueDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
Omar SaeedAlbert Einstein College of Medicine, Bronx, New York, USA.
Rachna KatariaDivision of Cardiology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Yoram A PuiusAlbert Einstein College of Medicine, Bronx, New York, USA.
Snehal R PatelAlbert Einstein College of Medicine, Bronx, New York, USA.
Mario J GarciaAlbert Einstein College of Medicine, Bronx, New York, USA.
Andrew D RacineAlbert Einstein College of Medicine, Bronx, New York, USA.
Daniel B SimsAlbert Einstein College of Medicine, Bronx, New York, USA.
Ulrich P JordeAlbert Einstein College of Medicine, Bronx, New York, USA ujorde@montefiore.org.

Funding

CTSA Administrative Supplement for Informatics Core: A novel AI/ML system to predict respiratory failure and ARDS in Covid-19 patientsUL1TR002556 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, KIM, MIMI Y · 2018 to 2022
$26.7M
Core-010UL1TR001073 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, SHAMOON, HARRY · 2013 to 2017
$21.3M
Mechanisms of cardiovascular diseaseT32HL144456 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Carlos Jose Rodriguez, Nicholas E Sibinga · 2019 to 2026
$1.9M
Hemolysis and Platelet Activation during Continuous Flow Mechanical Circulatory SupportK23HL145140 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SAEED, OMAR · 2019 to 2023
$840k
NCATS NIH HHS UL1 TR001073NCATS NIH HHS UL1 TR002556NHLBI NIH HHS K23 HL145140NHLBI NIH HHS T32 HL144456
6 · The paper itself

Abstract

introductionCOVID-19 first struck New York City in the spring of 2020, resulting in an unprecedented strain on our healthcare system and triggering multiple changes in public health policy governing hospital operations as well as therapeutic approaches to COVID-19. We examined inpatient mortality at our centre throughout the course of the pandemic.

methodsThis is a retrospective chart review of clinical characteristics, treatments and outcome data of all patients admitted with COVID-19 from 1 March 2020 to 28 February 2021. Patients were grouped into 3-month quartiles. Hospital strain was assessed as per cent of occupied beds based on a normal bed capacity of 1491.

resultsInpatient mortality decreased from 25.0% in spring to 10.8% over the course of the year. During this time, use of remdesivir, steroids and anticoagulants increased; use of hydroxychloroquine and other antibiotics decreased. Daily bed occupancy ranged from 62% to 118%. In a multivariate model with all year's data controlling for demographics, comorbidities and acuity of illness, percentage of bed occupancy was associated with increased 30-day in-hospital mortality of patients with COVID-19 (0.7% mortality increase for each 1% increase in bed occupancy; HR 1.007, CI 1.001 to 1.013, p=0.004)

conclusionInpatient mortality from COVID-19 was associated with bed occupancy. Early reduction in epicentre hospital bed occupancy to accommodate acutely ill and resource-intensive patients should be a critical component in the strategic planning for future pandemics.

Indexed as

COVID-19PandemicsBed OccupancyCohort StudiesHospital MortalityHospitalsHumansInpatientsIntensive Care UnitsRetrospective StudiesRisk FactorsSARS-CoV-2COVID-19epidemiologypublic health

Identifiers

PMID35168984
PMCPMC8852235

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.