Evidence map›Paper›PMID 35168978›Full record

ArticleBMJ open2022

Status of hospital-based blood transfusion services in low-income and middle-income countries: a cross-sectional international survey.

Linda S Barnes, Jean Stanley, Evan M Bloch, Monica B Pagano, Tina S Ipe, Quentin Eichbaum, Silvano Wendel, Alexander Indrikovs, Wei Cai, Meghan Delaney and 1 more

Abstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  19. Big Data in Transfusion Medicine and Artificial Intelligence Analysis for Red Blood Cell Quality Control.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Linda S BarnesDoctor of Public Health Leadership, University of Illinois--Chicago, Chicago, Illinois, USA lbarne23@gmail.com.ORCID 0000-0002-5090-0328
Jean StanleyQuality Focus, Moraga, California, USA.
Evan M BlochPathology, Johns Hopkins Medicine, Baltimore, Maryland, USA.
Monica B PaganoLaboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.
Tina S IpeDepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Quentin EichbaumPathology, Immunology and Microbiology | Medical Education and Administration, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Silvano WendelHospital Sirio Libanes Blood Bank, Sao Paulo, Brazil.
Alexander IndrikovsPathology, Northwell Health, Manhasset, New York, USA.
Wei CaiStanford Health Care, Stanford, California, USA.
Meghan DelaneyPathology and Laboratory Medicine, Children's National Hospital, Washington, District of Columbia, USA.
AABB Global Transfusion Forum

Funding

The Malaria Transfusion Risk (MATRix) StudyK23HL151826 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BLOCH, EVAN MARTIN · 2020 to 2024
$882k
NHLBI NIH HHS K23 HL151826
6 · The paper itself

Abstract

objectivesBlood transfusion is life-saving for patients experiencing acute blood loss and severe anaemia. In low-income and middle-income countries (LMICs), low blood donation rates and unavailability of whole blood and blood components (blood products) impairs timely blood transfusion. To fulfil patient-specific blood orders, a hospital blood transfusion service (HBTS) receives orders from a prescriber for blood transfusion, tests and prepares blood products for the patient. This study sought to describe the current state of LMIC HBTS.

designA cross-sectional survey explored LMIC HBTS access to blood products, testing methods, policies and structure. Surveys were administered in English, Spanish, French and Russian, followed by a mixed-methods analysis.

settingHBTS within LMICs.

participantsFrom among 124 public and private facilities invited to participate, we received 71 (57%) responses. Of these responses, 50 HBTS from 27 LMICs performed on-site blood transfusions.

resultsMost LMIC HBTS perform blood collection to generate blood products for their patients (36/47, 77%); few relied exclusively on an external supply of blood products (11/47, 23%). The primary reason for blood transfusion was adult anaemia for non-malignant conditions (17/112, 15%). Testing methods varied by gross national income per capita. Blood transfusion delays to patients were common (17/30, 57%) attributed to inadequate blood inventories (13/29, 45%). Other barriers included lack of regular clinician education about transfusion (8/29, 28%) and sustainable financial models for the HBTS (4/29, 14%).

conclusionThis survey describes the status of HBTS in diverse LMICs, illustrating that the availability of blood products remains a principal problem, requiring HBTS to generate its own facility's blood supply. Currently, blood shortages are not reported as a patient-specific adverse event making systematic tracking of delays in transfusion difficult. These findings highlight areas for further exploration related to the lack of available blood inventories for transfusions at HBTS in LMICs.

Indexed as

Developing CountriesPovertyAdultBlood TransfusionCross-Sectional StudiesHospitalsHumansblood bank & transfusion medicinehealth policyhealth services administration & managementorganisation of health servicespublic health

Identifiers

PMID35168978
PMCPMC8852762

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.