Evidence map›Paper›PMID 35168950›Full record

ArticleeNeuro

Contributions of Distinct Auditory Cortical Inhibitory Neuron Types to the Detection of Sounds in Background Noise.

Anna A Lakunina, Nadav Menashe, Santiago Jaramillo

Open access · greenAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Distinct Inhibitory Neurons Differently Shape Neuronal Codes for Sound Intensity in the Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  6. Article
  7. Article
  8. Developmental hearing loss-induced perceptual deficits are rescued by genetic restoration of cortical inhibition.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anna A LakuninaInstitute of Neuroscience and Department of Biology, University of Oregon, Eugene, Oregon 97403.ORCID 0000-0003-2628-8834
Nadav MenasheInstitute of Neuroscience and Department of Biology, University of Oregon, Eugene, Oregon 97403.
Santiago JaramilloInstitute of Neuroscience and Department of Biology, University of Oregon, Eugene, Oregon 97403 sjara@uoregon.edu.ORCID 0000-0002-6595-8450
University of Oregon · US

Funding

Contribution of distinct auditory pathways to sound-driven choices.R01DC015531 · NIDCD · UNIVERSITY OF OREGON · PI JARAMILLO, SANTIAGO · 2016 to 2020
$1.6M
Contributions of distinct auditory pathways to sound-driven choicesR56DC015531 · NIDCD · UNIVERSITY OF OREGON · PI JARAMILLO, SANTIAGO, MURRAY, JAMES · 2022 to 2022
$145k
NIDCD NIH HHS R01 DC015531NIDCD NIH HHS R56 DC015531
6 · The paper itself

Abstract

The ability to separate background noise from relevant acoustic signals is essential for appropriate sound-driven behavior in natural environments. Examples of this separation are apparent in the auditory system, where neural responses to behaviorally relevant stimuli become increasingly noise invariant along the ascending auditory pathway. However, the mechanisms that underlie this reduction in responses to background noise are not well understood. To address this gap in knowledge, we first evaluated the effects of auditory cortical inactivation on mice of both sexes trained to perform a simple auditory signal-in-noise detection task and found that outputs from the auditory cortex are important for the detection of auditory stimuli in noisy environments. Next, we evaluated the contributions of the two most common cortical inhibitory cell types, parvalbumin-expressing (PV

Indexed as

Auditory CortexAcoustic StimulationAnimalsAuditory PerceptionFemaleInterneuronsMaleMiceNeuronsNoiseParvalbuminsParvalbuminsauditory cortexcortical inhibitionsensory processingsignal detection

Identifiers

PMID35168950
PMCPMC8906447
OpenAlexW4220781032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.