Evidence map›Paper›PMID 35168899›Full record

ArticleThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2022

Patient factors associated with left ventricular assist device infections: A scoping review.

Michael J Pienta, Supriya Shore, Tessa M F Watt, Gardner Yost, Whitney Townsend, Lourdes Cabrera, Michael D Fetters, Carol Chenoweth, Keith Aaronson, Francis D Pagani and 2 more

Open access · greenAbstract readScoping Review
In one paragraph

Article in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Infections following left ventricular assist device implantation and 1-year health-related quality of life.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Michael J PientaDepartment of Cardiac Surgery. Electronic address: mpienta@med.umich.edu.
Supriya ShoreDivision of Cardiovascular Medicine.
Tessa M F WattDepartment of Cardiac Surgery.
Gardner YostDepartment of Cardiac Surgery.
Whitney TownsendDepartment of Cardiac Surgery.
Lourdes CabreraDepartment of Cardiac Surgery.
Michael D FettersMixed Methods Program and Department of Family Medicine.
Carol ChenowethDivision of Infectious Diseases, University of Michigan, Ann Arbor, Michigan.
Keith AaronsonDivision of Cardiovascular Medicine.
Francis D PaganiDepartment of Cardiac Surgery.
Donald S LikoskyDepartment of Cardiac Surgery.
Michigan Congestive Heart Failure Investigators
San Diego Cardiac Center · USUniversity of Michigan · US

Funding

Understanding and Addressing Variation in Healthcare-Associated Infections After Durable Ventricular Assist Device TherapyR01HS026003 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIKOSKY, DONALD S · 2018 to 2022
$2.3M
AHRQ HHS R01 HS026003
6 · The paper itself

Abstract

Infections are widely prevalent in left ventricular assist device (LVAD) recipients and associated with adverse events including mortality and rehospitalizations. Current evidence examining factors associated with infections in this setting predominantly comprises single-center observational data. We performed a scoping review to systematically summarize all existing studies examining patient-related factors associated with infections after LVAD implantation. Studies published between 01/06 and 02/19 were identified through searching 5 bibliographic databases: PubMed, Scopus, EMBASE, CINAHL, and Web of Science Core Collection. Inclusion criteria required examination of patient-related factors associated with infections among recipients of contemporary implantable, continuous flow LVADs. Key study characteristics were extracted by four independent reviewers and current literature described narratively. All analyses took place between February 2019 and May 2021. A total of 31 studies met inclusion criteria. All included studies were observational, and most commonly focused on driveline infections (n = 17). Factors studied most commonly included body composition (n = 8), diabetes and other comorbidities (n = 8), and psychosocial/socio-economic factors (n = 6). Studies were frequently single-center with heterogeneity in definition of infectious outcomes as well as exposure variables. Patient race and sex did not correlate with infection risk. There was no consistent association noted between obesity, diabetes, or psychosocial/socio-economic factors and infections in LVAD recipients. Two studies reported a significant association between malnutrition and hypoalbuminemia and post implant infections. This review summarizes 31 studies that described patient-related factors associated with infection after LVAD implantation. Patient related comorbidities, especially body composition and diabetes, were most commonly evaluated, but were not consistently associated with infections after LVAD implantation.

Indexed as

Heart-Assist DevicesHeart FailureComorbidityHumansRetrospective Studiescomplicationsinfectionleft ventricular assist devicemorbidityquality

Identifiers

PMID35168899
PMCPMC9974018
OpenAlexW4205967868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.