Evidence map›Paper›PMID 35168886›Full record

ArticleGenetics in medicine : official journal of the American College of Medical Genetics2022

Correspondence on "Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database" by Dominguez-Valentin et al.

Ramadhani Chambuso, Evelyn Kaambo, George Rebello, Raj Ramesar

Registry-linked trialAbstract readLetterComment
PubMed Publisher
In one paragraph

Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06708429 (Impact of Immune-surveillance on the Development of Colorectal Cancer in Patients With Lynch Syndrome), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06708429 recruitingnot on this mapstarted 2023, after this paper: background citation

Impact of Immune-surveillance on the Development of Colorectal Cancer in Patients With Lynch Syndrome

TypeobservationalSponsorSan Raffaele UniversityRan2023 to 2034Enrolled300ConditionsLynch Syndrome, Lynch Syndrome I, Lynch Syndrome II, Lynch Syndrome I (Site-specific Colonic Cancer)ArmsLYNX EYE (Lynch syndrome X-Talk of Enteral mucosa with Immune System)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Ramadhani ChambusoDivision of Human Genetics, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; MRC Unit for Genomic and Precision Medicine, Division of Human Genetics, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. Electronic address: ramadhani.chambuso@uct.ac.za.
Evelyn KaamboDepartment of Biochemistry and Medical Microbiology, School of Medicine, University of Namibia, Windhoek, Namibia; Division of Medical Virology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
George RebelloDivision of Human Genetics, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; MRC Unit for Genomic and Precision Medicine, Division of Human Genetics, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Raj RamesarDivision of Human Genetics, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; MRC Unit for Genomic and Precision Medicine, Division of Human Genetics, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; Division of Human Genetics, Department of Pathology, Colorectal Cancer Research Group, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Colorectal Neoplasms, Hereditary NonpolyposisDNA Mismatch RepairHeterozygoteHumansMismatch Repair Endonuclease PMS2MutL Protein Homolog 1MutS Homolog 2 ProteinProspective StudiesMismatch Repair Endonuclease PMS2MutL Protein Homolog 1MutS Homolog 2 Protein

Identifiers

PMID35168886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.