Evidence map›Paper›PMID 35168614›Full record

ArticleMicrobial cell factories2022

Development of a novel expression system in lactic acid bacteria controlled by a broad-host-range promoter P

Chengran Guan, Yuan Yuan, Yan Ma, Xin Wang, Chenchen Zhang, Maolin Lu, Ruixia Gu, Dawei Chen

Abstract read
In one paragraph

Article in Microbial cell factories, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. A Safe and Versatile Minicell Platform Derived fromJournal of microbiology and biotechnology · 2025
    Article
  3. Review
  4. Review
  5. Development of ZnSynthetic and systems biotechnology · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chengran GuanKey Lab of Dairy Biotechnology and Safety Control, College of Food Science and Technology, Yangzhou University, Yangzhou, 225127, Jiangsu, China.
Yuan YuanKey Lab of Dairy Biotechnology and Safety Control, College of Food Science and Technology, Yangzhou University, Yangzhou, 225127, Jiangsu, China.
Yan MaKey Lab of Dairy Biotechnology and Safety Control, College of Food Science and Technology, Yangzhou University, Yangzhou, 225127, Jiangsu, China.
Xin WangShandong Yinfeng Life Science Research Institute, Jinan, 250000, Shandong, China.
Chenchen ZhangKey Lab of Dairy Biotechnology and Safety Control, College of Food Science and Technology, Yangzhou University, Yangzhou, 225127, Jiangsu, China.
Maolin LuKey Lab of Dairy Biotechnology and Safety Control, College of Food Science and Technology, Yangzhou University, Yangzhou, 225127, Jiangsu, China.
Ruixia GuKey Lab of Dairy Biotechnology and Safety Control, College of Food Science and Technology, Yangzhou University, Yangzhou, 225127, Jiangsu, China.
Dawei ChenKey Lab of Dairy Biotechnology and Safety Control, College of Food Science and Technology, Yangzhou University, Yangzhou, 225127, Jiangsu, China. 444306783@qq.com.ORCID http://orcid.org/0000-0002-6668-6434

Funding

National Natural Science Foundation of China 31700079Natural Science Foundation of Jiangsu Province BK20170496
6 · The paper itself

Abstract

backgroundLatic acid bacteria (LAB) are exploited for development of gene expression system owing to its health promoting properties and a high degree of safety status. Most of the expression systems were constructed in Lactobacillus lactis with inducible promoters. It is necessary to exploit novel promoters to develop LAB host platforms which are indispensable in dairy and health application to satisfy the production demand of increased number of target-genes. Previously, promoter P

resultsPlasmid with the green fluorescent protein (GFP) inserting downstream of P

conclusionsThese data suggested that P

Indexed as

Gene ExpressionHost SpecificityPromoter Regions, GeneticBacterial ProteinsEscherichia coliGreen Fluorescent ProteinsLactobacillalesPlasmidsBacterial ProteinsGreen Fluorescent ProteinsBroad-host-ranged promoterExpression systemHeterologous expressionLactic acid bacteria

Identifiers

PMID35168614
PMCPMC8845276

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.