Evidence map›Paper›PMID 35168501›Full record

Observational studyRenal failure2022

The predictive value of the Oxford Acute Severity of Illness Score for clinical outcomes in patients with acute kidney injury.

Na Wang, Meiping Wang, Li Jiang, Bin Du, Bo Zhu, Xiuming Xi

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Renal failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Na WangEmergency Department of China Rehabilitation Research Center, Capital Medical University, Beijing, China.
Meiping WangDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China.
Li JiangDepartment of Critical Care Medicine, Xuan Wu Hospital, Capital Medical University, Beijing, China.
Bin DuMedical Intensive Care Unit, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Bo ZhuDepartment of Critical Care Medicine, Fu Xing Hospital, Capital Medical University, Beijing, China.
Xiuming XiDepartment of Critical Care Medicine, Fu Xing Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the performance of the Oxford Acute Severity of Illness Score (OASIS), the Acute Physiology and Chronic Health Evaluation II (APACHE II) score, the Simplified Acute Physiology Score II (SAPS II), and the Sequential Organ Failure Assessment (SOFA) score in predicting 28-day mortality in acute kidney injury (AKI) patients.

methodsData were extracted from the Beijing Acute Kidney Injury Trial (BAKIT). A total of 2954 patients with complete clinical data were included in this study. Receiver operating characteristic (ROC) curves were used to analyze and evaluate the predictive effects of the four scoring systems on the 28-day mortality risk of AKI patients and each subgroup. The best cutoff value was identified by the highest combined sensitivity and specificity using Youden's index.

resultsAmong the four scoring systems, the area under the curve (AUC) of OASIS was the highest. The comparison of AUC values of different scoring systems showed that there were no significant differences among OASIS, APACHE II, and SAPS II, which were better than SOFA. Moreover, logistic analysis revealed that OASIS was an independent risk factor for 28-day mortality in AKI patients. OASIS also had good predictive ability for the 28-day mortality of each subgroup of AKI patients.

conclusionOASIS, APACHE II, and SAPS II all presented good discrimination and calibration in predicting the 28-day mortality risk of AKI patients. OASIS, APACHE II, and SAPS II had better predictive accuracy than SOFA, but due to the complexity of APACHE II and SAPS II calculations, OASIS is a good substitute.

trial registrationThis study was registered at www.chictr.org.cn (registration number Chi CTR-ONC-11001875). Registered on 14 December 2011.

Indexed as

Acute Kidney InjuryAPACHEOrgan Dysfunction ScoresSimplified Acute Physiology ScoreAgedAged, 80 and overBeijingFemaleHospital MortalityHumansIntensive Care UnitsLogistic ModelsMaleMiddle AgedPrognosisProspective StudiesAKIintensive care unitmortalityOxford Acute Severity of Illness Score

Identifiers

PMID35168501
PMCPMC8856098

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.