SynthesisJournal of enzyme inhibition and medicinal chemistry2022
Antibacterial action mechanisms and mode of trypsin inhibitors: a systematic review.
Synthesis in Journal of enzyme inhibition and medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Acid precipitation salting out as an efficient strategy for high purity potato trypsin inhibitor recovery.NPJ science of food · 2026Article
- The biological control potential of extracellular protein from Bacillus velezensis against Ralstonia solanacearum in tomatoes.Archives of microbiology · 2026Article
- Bifunctional Peptides Generated by Optimising the Antimicrobial Activity of a Novel Trypsin-Inhibitory Peptide fromBiomolecules · 2026Article
- Effect of trypsin inhibitor isolated from tamarind seed (TTI) on caenorhabditis elegans survival under bacterial infection.Journal of enzyme inhibition and medicinal chemistry · 2025Article
- Infiltration-RNAseq Reveals Enhanced Defense Responses inPlants (Basel, Switzerland) · 2025Article
- Analysis of Protein Inhibitors of Trypsin in Quinoa, Amaranth and Lupine Seeds. Selection and Deep Structure-Function Characterization of theInternational journal of molecular sciences · 2025Article
- Proteomic Characterization of a Lunasin-Enriched Soybean Extract Potentially Useful in the Treatment ofNutrients · 2024Article
- Plant Protease Inhibitors as Emerging Antimicrobial Peptide Agents: A Comprehensive Review.Pharmaceutics · 2024Review
- Antiviral Drug Candidate Repositioning forBiomedicines · 2024Article
- Innovative Biomedical and Technological Strategies for the Control of Bacterial Growth and Infections.Biomedicines · 2024Review
- ProspectingJournal of enzyme inhibition and medicinal chemistry · 2023Article
- Di-Arginine Additives for Dissociation of Gold Nanoparticle Aggregates: A Matrix-Insensitive Approach with Applications in Protease Detection.ACS applied materials & interfaces · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This systematic review (SR) aimed to gather studies describing the antibacterial action mechanisms and mode of trypsin inhibitors. The review protocol was registered (PROSPERO: CRD42020189069). Original articles resulting from studies in animal models, in bacterial culture, and using cells that describe antibacterial action of trypsin inhibitor-type peptides or proteins were selected in PubMed, Science Direct, Scopus, Web of Science, BVS, and EMBASE. The methodological quality assessment was performed using the PRISMA and OHAT tool. 2382 articles were retrieved, 17 of which were eligible. Four studies demonstrated the action mechanism directly on the bacterial membrane, and the fifth study on endogenous proteases extracted from the bacteria themselves. The antibacterial action mode was presented in the other studies, which can generate bacteriostatic or bactericidal effects without describing the mechanisms. This study generated information to enable new preclinical or clinical studies with molecules contributing to public health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.