Evidence map›Paper›PMID 35168136›Full record

ArticleJournal of clinical anesthesia2022

Association between alcohol use disorder and hospital outcomes in colectomy patients - A retrospective cohort study.

Megan L Rolfzen, Susan K Mikulich-Gilbertson, Crystal Natvig, Jacqueline A Carrico, Robert L Lobato, Martin Krause, Karsten Bartels

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical anesthesia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Megan L RolfzenDepartment of Anesthesiology, University of Nebraska Medical Center, Omaha, NE, USA.
Susan K Mikulich-GilbertsonDepartment of Psychiatry, University of Colorado, School of Medicine, Aurora, CO, USA.
Crystal NatvigDepartment of Psychiatry, University of Colorado, School of Medicine, Aurora, CO, USA.
Jacqueline A CarricoDepartment of Anesthesiology, University of Colorado School of Medicine, Aurora, CO, USA.
Robert L LobatoDepartment of Anesthesiology, University of Nebraska Medical Center, Omaha, NE, USA.
Martin KrauseDepartment of Anesthesiology, University of California, San Diego, CA, USA.
Karsten BartelsDepartment of Anesthesiology, University of Nebraska Medical Center, Omaha, NE, USA; Outcomes Research Consortium, Cleveland, OH, USA. Electronic address: karbartels@unmc.edu.
University of Colorado Denver · USUniversity of Nebraska Medical Center · USUniversity of California, San Diego · US

Funding

Improving Opioid Prescription Safety After SurgeryK23DA040923 · NIDA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BARTELS, KARSTEN · 2016 to 2020
$945k
AHRQ HHS R01 HS027795NIDA NIH HHS K23 DA040923
6 · The paper itself

Abstract

STUDY

objectiveIn the United States, alcohol use disorder adversely affects 5.6% of all adults. Excessive alcohol consumption adversely affects organ functions critical for adaptation to stress induced by surgery. Colorectal resection is one of the most common major surgeries in patients at risk for alcohol use disorder. The objective of this study was to assess the impact of alcohol use disorder on hospital outcomes after colectomy using a population-based discharge database.

settingPopulation-based discharge database. PATIENTS: The Premier Healthcare Database was queried for the 603,730 adult patients who underwent colectomy from 2016 to 2019.

interventionsNone. MEASUREMENTS: Multiple logistic regressions estimated the associations between in-hospital mortality, length of stay, and hospitalization cost with alcohol use disorder as the primary predictor, adjusting for other substance use disorders, psychotic disorders, depression, other Elixhauser comorbidities, age, payor, race, gender, non-elective surgery, and other unbalanced variables. MAIN

resultsA discharge code for alcohol use disorder was identified in 2.9% of colectomy patients and the overall in-hospital mortality rate in all sampled colectomy patients was 1.4%. Alcohol use disorder was associated with a significantly increased risk of in-hospital mortality after adjusting for other factors (AOR 1.36, 95% CI 1.24-1.48, p < 0.0001). Alcohol use disorder was also significantly associated with long length of stay (AOR 1.45, 95% CI 1.39-1.52, p < 0.0001) and high hospitalization costs (AOR 1.63, 95% CI 1.56-1.70, p < 0.0001).

conclusionsAlcohol use disorder is associated with an increased risk of in-hospital mortality in patients undergoing colectomy, one of the most common major surgeries. Future research should examine if enhanced efforts to identify patients with alcohol use disorder could enable anesthesiologists to provide worthwhile perioperative interventions for this high-risk population.

Indexed as

AlcoholismAdultAlcohol DrinkingColectomyHospital MortalityHospitalsHumansLength of StayRetrospective StudiesUnited StatesAlcohol use disorderColectomyDepressionIn-hospital mortalityPsychotic disorderSubstance use disorder

Identifiers

PMID35168136
PMCPMC13614720
OpenAlexW4211126180

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.