Evidence map›Paper›PMID 35167950›Full record

ReviewThe ocular surface2022

Ocular surface disease in thyroid eye disease: A narrative review.

Harkaran S Rana, Sruti S Akella, Carson E Clabeaux, Zachary P Skurski, Vinay K Aakalu

Open access · greenAbstract readReview
In one paragraph

Review in The ocular surface, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.

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  18. Investigation of lacrimal gland and extraocular muscle in thyroid eye disease patients with severe subjective dry eye disease: a multiparametric magnetic resonance imaging study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Harkaran S RanaDepartment of Ophthalmology, Walter Reed National Military Medical Center, Bethesda, MD, United States.
Sruti S AkellaDepartment of Ophthalmology and Visual Sciences, University of Illinois-Chicago, Chicago, IL, United States.
Carson E ClabeauxDepartment of Ophthalmology, Madigan Army Medical Center, Tacoma, WA, United States.
Zachary P SkurskiDepartment of Ophthalmology, Keller Army Community Hospital, West Point, NY, United States.
Vinay K AakaluDepartment of Ophthalmology and Visual Sciences, University of Illinois-Chicago, Chicago, IL, United States. Electronic address: vaakalu@uic.edu.
University of Illinois Urbana-Champaign · USKeller Army Community Hospital · USMadigan Army Medical Center · USWalter Reed National Military Medical Center · US

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AAKALU, VINAY · 1985 to 2025
$14.8M
Novel Treatments for Ocular Surface DiseasesR01EY029409 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI AAKALU, VINAY · 2019 to 2023
$1.9M
NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY029409
6 · The paper itself

Abstract

Ocular surface disease (OSD) in the setting of thyroid eye disease (TED) is traditionally thought of as a natural consequence of anatomical changes such as proptosis and corneal exposure. However, a growing body of research suggests that ocular surface inflammation and multi-factorial changes to the homeostasis of the ocular surface contribute substantially to the OSD seen in TED patients. In this paper we review the existing literature which highlights the work and existing theories underlying this new paradigm shift.

Indexed as

Graves OphthalmopathyEyeHumansDry eyeExposure keratopathyOcular surface diseaseThyroid eye disease

Identifiers

PMID35167950
PMCPMC9058200
OpenAlexW4213351677

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.