Evidence map›Paper›PMID 35167774›Full record

ArticleJournal of the Royal Society, Interface2022

Evaluating strategies for spatial allocation of vaccines based on risk and centrality.

Benjamin J Singer, Robin N Thompson, Michael B Bonsall

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Benjamin J SingerDepartment of Zoology, University of Oxford, Oxford, UK.ORCID 0000-0003-3062-2620
Robin N ThompsonMathematics Institute, University of Warwick, Coventry, UK.ORCID 0000-0001-8545-5212
Michael B BonsallDepartment of Zoology, University of Oxford, Oxford, UK.ORCID 0000-0003-0250-0423

Funding

Biotechnology and Biological Sciences Research Council BB/M011224/1
6 · The paper itself

Abstract

When vaccinating a large population in response to an invading pathogen, it is often necessary to prioritize some individuals to be vaccinated first. One way to do this is to choose individuals to vaccinate based on their location. Methods for this prioritization include strategies that target those regions most at risk of importing the pathogen, and strategies that target regions with high centrality on the travel network. We use a simple infectious disease epidemic model to compare a risk-targeting strategy to two different centrality-targeting strategies based on betweenness centrality and random walk percolation centrality, respectively. We find that the relative effectiveness of these strategies in reducing the total number of infections varies with the basic reproduction number of the pathogen, travel rates, structure of the travel network and vaccine availability. We conclude that when a pathogen has high spreading capacity, or when vaccine availability is limited, centrality-targeting strategies should be considered as an alternative to the more commonly used risk-targeting strategies.

Indexed as

Communicable DiseasesEpidemicsVaccinesBasic Reproduction NumberHumansTravelVaccinesepidemic modellingmetapopulation modellingnetwork centralityvaccine strategy

Identifiers

PMID35167774
PMCPMC8847001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.