Evidence map›Paper›PMID 35167726›Full record

ArticleMaternal & child nutrition2022

Influence of exclusive breastfeeding on hippocampal structure, satiety responsiveness, and weight status.

Ryan C Higgins, Kathleen L Keller, Jane C Aruma, Travis D Masterson, Shana Adise, Nicole Fearnbach, Wendy M Stein, Laural K English, Bari Fuchs, Alaina L Pearce

Open access · goldAbstract read
In one paragraph

Article in Maternal & child nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Structural and Functional Brain Changes in Children and Adolescents With Obesity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ryan C HigginsPennsylvania State College of Medicine, University Park Campus, Hershey, Pennsylvania, USA.ORCID 0000-0002-9713-6945
Kathleen L KellerDepartment of Nutritional Sciences, Pennsylvania State University, State College, Pennsylvania, USA.
Jane C ArumaPennsylvania State College of Medicine, University Park Campus, Hershey, Pennsylvania, USA.
Travis D MastersonDepartment of Nutritional Sciences, Pennsylvania State University, State College, Pennsylvania, USA.
Shana AdiseDepartment of Nutritional Sciences, Pennsylvania State University, State College, Pennsylvania, USA.
Nicole FearnbachDepartment of Nutritional Sciences, Pennsylvania State University, State College, Pennsylvania, USA.
Wendy M SteinDepartment of Nutritional Sciences, Pennsylvania State University, State College, Pennsylvania, USA.
Laural K EnglishDepartment of Nutritional Sciences, Pennsylvania State University, State College, Pennsylvania, USA.
Bari FuchsDepartment of Nutritional Sciences, Pennsylvania State University, State College, Pennsylvania, USA.
Alaina L PearceDepartment of Nutritional Sciences, Pennsylvania State University, State College, Pennsylvania, USA.ORCID 0000-0003-3157-6566
Pennsylvania State University · USHershey (United States) · USPennington Biomedical Research Center · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Leigh Lamonica · 2012 to 2026
$69.1M
Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
Penn State Institutional Career Development CoreKL2TR002015 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI VAN SCOY, LAUREN JODI · 2016 to 2025
$7.8M
Brain Mechanisms of Overeating in ChildrenR01DK110060 · NIDDK · PENNSYLVANIA STATE UNIVERSITY, THE · PI KELLER, KATHLEEN L · 2017 to 2021
$2.4M
Determining protective cognitive and eating behavior phenotypes for pediatric obesityF32DK122669 · NIDDK · PENNSYLVANIA STATE UNIVERSITY, THE · PI PEARCE, ALAINA LUNDBERG · 2019 to 2021
$168k
NCATS NIH HHS KL2 TR002015NCATS NIH HHS UL1 TR000127NCATS NIH HHS UL1 TR002014NIDDK NIH HHS F32 DK122669NIDDK NIH HHS R01 DK110060NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Longer exclusive breastfeeding duration has been associated with differences in neural development, better satiety responsiveness, and decreased risk for childhood obesity. Given hippocampus sensitivity to diet and potential role in the integration of satiety signals, hippocampus may play a role in these relationships. We conducted a secondary analysis of 149, 7-11-year-olds (73 males) who participated in one of five studies that assessed neural responses to food cues. Hippocampal grey matter volume was extracted from structural scans using CAT12, weight status was assessed using age- and sex-adjusted body mass index (%BMI

Indexed as

Breast FeedingBody Mass IndexChildFemaleHippocampusHumansMalePediatric ObesityPregnancySatiety ResponseTime Factorsbrainbreastfeedingchildfeeding behaviorgrey matterhippocampusobesity

Identifiers

PMID35167726
PMCPMC9218327
OpenAlexW4213311211

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.