ReviewThe Plant cell2022
Thirty years of resistance: Zig-zag through the plant immune system.
Review in The Plant cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 463 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
463 citing papers in PubMed, 1 synthesis or guideline pooled it, 893 citations in OpenAlex.
- Research Progress of Peach Bacterial Spot Disease.International journal of molecular sciences · 2026Pooled it
- Chitosan activates a sequential CaPlant signaling & behavior · 2026Article
- Identifying anthracnose resistance genes involving in ROS and JA accumulation.Plant signaling & behavior · 2026Article
- First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea.Pest management science · 2026Article
- N-glycosylation code diversifies paralogous chitinases to balance plant immunity and growth.Nature plants · 2026Article
- Apoplast Engineering Unveiled: Multi-Target Strategies to Disarm Pathogens and Elevate Global Food Security.Plant, cell & environment · 2026Review
- A Ralstonia solanacearum effector RipAD perturbs aquaporin NbPIP oligomeric status to suppress plant immunity.The Plant journal : for cell and molecular biology · 2026Article
- The MdERF1B-miR482c-Horticulture research · 2026Article
- Insights Into the Role of Lysine Acetylation of Non-Histone Proteins in Plant Immunity.Plant, cell & environment · 2026Review
- Plant immune co-receptors: bridging gaps toward next-generation crop defense.Stress biology · 2026Review
- Comparative Transcriptomics Reveals Defense Mechanisms AgainstPlants (Basel, Switzerland) · 2026Article
- Molecular Bases and Genetic Design of Rice Disease Resistance for Optimized Yield and Sustainable Agriculture.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Cysteine-rich secreted protein OsCRRSP1 enhances rice defense through dual inhibition of pathogen and host catalases.Plant communications · 2026Article
- Hos2-mediated KatG1 decrotonylation orchestrates ROS scavenging in rice blast infection.Nature communications · 2026Article
- Review
- LURP1, a SARD1-regulated protein, coordinates with the helper NLR ADR1 to promote plant immunity.The New phytologist · 2026Article
- E3 ubiquitin ligases in plant defense: mechanisms and prospects for resistance breeding.Science China. Life sciences · 2026Review
- Integrated Functional Characterization of Hemileia vastatrix Effector Candidates Reveals Coordinated Immune Suppression, Sequential Deployment and Compartment-Specific Targeting.Molecular plant pathology · 2026Article
- Volatile Organic Compounds Emitted by Fungi Have Substantial Effects on Growth and Disease Resistance in Arabidopsis thaliana.Plant, cell & environment · 2026Article
- A Rhamnogalacturonan Acetylesterase Effector FsRGAE1 Enhances the Virulence ofJournal of fungi (Basel, Switzerland) · 2026Article
403 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 3 countries.
Funding
Abstract
Understanding the plant immune system is crucial for using genetics to protect crops from diseases. Plants resist pathogens via a two-tiered innate immune detection-and-response system. The first plant Resistance (R) gene was cloned in 1992 . Since then, many cell-surface pattern recognition receptors (PRRs) have been identified, and R genes that encode intracellular nucleotide-binding leucine-rich repeat receptors (NLRs) have been cloned. Here, we provide a list of characterized PRRs and NLRs. In addition to immune receptors, many components of immune signaling networks were discovered over the last 30 years. We review the signaling pathways, physiological responses, and molecular regulation of both PRR- and NLR-mediated immunity. Recent studies have reinforced the importance of interactions between the two immune systems. We provide an overview of interactions between PRR- and NLR-mediated immunity, highlighting challenges and perspectives for future research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.