Evidence map›Paper›PMID 35167409›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

Cyclosporin A Reveals Potent Antiviral Effects in Preclinical Models of SARS-CoV-2 Infection.

Lucie Sauerhering, Irina Kuznetsova, Alexandra Kupke, Lars Meier, Sandro Halwe, Cornelius Rohde, Jörg Schmidt, Rory E Morty, Olga Danov, Armin Braun and 3 more

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Preparing for the next viral threat with broad-spectrum antivirals.The Journal of clinical investigation · 2023
    Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lucie SauerheringPhilipps University of Marburg Marburg, Germany.ORCID 0000-0001-5487-3243
Irina KuznetsovaUniversity of Giessen Giessen, Germany.
Alexandra KupkePhilipps University of Marburg Marburg, Germany.ORCID 0000-0001-8517-4779
Lars MeierPhilipps University of Marburg Marburg, Germany.
Sandro HalwePhilipps University of Marburg Marburg, Germany.ORCID 0000-0002-4021-7728
Cornelius RohdePhilipps University of Marburg Marburg, Germany.ORCID 0000-0002-4752-8326
Jörg SchmidtPhilipps University of Marburg Marburg, Germany.
Rory E MortyUniversity of Giessen Giessen, Germany.ORCID 0000-0003-0833-9749
Olga DanovGerman Center for Lung Research Giessen, Germany.ORCID 0000-0001-6860-5610
Armin BraunGerman Center for Lung Research Giessen, Germany.ORCID 0000-0002-1142-1463
István VadászUniversity of Giessen Giessen, Germany.ORCID 0000-0003-1370-9783
Stephan BeckerPhilipps University of Marburg Marburg, Germany.
Susanne HeroldGerman Center for Infection Research Braunschweig, Germany.ORCID 0000-0001-6343-0911

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19 Drug TreatmentCyclosporineAntiviral AgentsDrug Evaluation, PreclinicalHumansSARS-CoV-2Antiviral AgentsCyclosporine

Identifiers

PMID35167409
PMCPMC9838622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.