ArticleApplied biochemistry and biotechnology2023
Antibiofilm Effect of Curcumin Against Staphylococcus aureus Surface Wound Biofilm-Associated Infection: In Vitro and In Silico.
Article in Applied biochemistry and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Beyond the Rhizome: Phytochemistry, Biological Activities, and Sustainable Utilization ofPharmaceuticals (Basel, Switzerland) · 2026Review
- Antimicrobial effects of compound Huangbai liquid onAmerican journal of translational research · 2026Article
- Review
- Pharmacological effects, formulations, and clinical research progress of curcumin.Frontiers in pharmacology · 2025Review
- Natural compounds in the fight againstFrontiers in pharmacology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biofilm is the consortia of the sessile group of microbial species that are adhered to the biotic and abiotic surfaces with the help of extracellular polymeric substances (EPS) and glycocalyx. A wound is a lesion on the epidermal surface that exposes the underlying tissues to the external environment and thus forms a region of proliferation for several species of Staphylococcus aureus. S. aureus is the most commonly observed nosocomial biofilm-forming organism that is responsible for the development of wound-associated infections. The biofilm prevents the penetration of the drug molecules thereby resulting in the development of antibiotic and multi-drug resistance among the organism. Thus, the use of alternative therapeutics has paved the path in the treatment of biofilm-associated infections. Curcumin has been used for the purpose of treating various illnesses from time immemorial. In this study, we observed that curcumin was able to bring about a reduction in the biofilm formed by S. aureus in the wound infection among the patients. The in silico studies revealed that curcumin possessed the ability to bring about interaction with the biofilm-forming proteins of S. aureus effectively.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.