Evidence map›Paper›PMID 35166326›Full record

ReviewBiochemical Society transactions2022

Whole-genome methods to define DNA and histone accessibility and long-range interactions in chromatin.

Luke T Marr, Prasoon Jaya, Laxmi N Mishra, Jeffrey J Hayes

Open access · greenAbstract readReview
In one paragraph

Review in Biochemical Society transactions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Luke T MarrDepartment of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY 14642, U.S.A.
Prasoon JayaDepartment of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY 14642, U.S.A.
Laxmi N MishraDepartment of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY 14642, U.S.A.
Jeffrey J HayesDepartment of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY 14642, U.S.A.ORCID 0000-0001-6981-1803
Albert Einstein College of Medicine · USUniversity of Rochester Medical Center · US

Funding

Histone Tall Interactions and Functions in ChromatinR01GM052426 · NIGMS · UNIVERSITY OF ROCHESTER · PI HAYES, JEFFREY J · 1995 to 2021
$6.2M
Training in Cellular, Biochemical and Molecular SciencesT32GM068411 · NIGMS · UNIVERSITY OF ROCHESTER · PI MAQUAT, LYNNE E · 2005 to 2019
$3.9M
NIGMS NIH HHS R01 GM052426NIGMS NIH HHS T32 GM068411
6 · The paper itself

Abstract

Defining the genome-wide chromatin landscape has been a goal of experimentalists for decades. Here we review highlights of these efforts, from seminal experiments showing discontinuities in chromatin structure related to gene activation to extensions of these methods elucidating general features of chromatin related to gene states by exploiting deep sequencing methods. We also review chromatin conformational capture methods to identify patterns in long-range interactions between genomic loci.

Indexed as

ChromatinHistonesChromosomesDNAGenomeHigh-Throughput Nucleotide SequencingSequence Analysis, DNAChromatinDNAHistonesATAC-seqCHIA-PETCHIP-seqFAIREHiCwhole-genome techniques

Identifiers

PMID35166326
PMCPMC9847230
OpenAlexW4212934166

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.