Evidence map›Paper›PMID 35166210›Full record

ArticleBiomedical journal2021

The effects of bone-substitute augmentation on treatment of osteoporotic intertrochanteric fractures.

Fu-Chun Chang, Pao-Yao Chuang, Ching-Yu Lee, Chien-Yin Lee, Ying-Chao Chou, Tsan-Wen Huang, Kuo-Chin Huang, Hsin-Nung Shih, Mel S Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Fu-Chun ChangDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital at Yunlin, Yunlin, Taiwan.
Pao-Yao ChuangDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan.
Ching-Yu LeeDepartment of Orthopedics, Taipei Medical University Hospital, Taipei, Taiwan.
Chien-Yin LeeDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan.
Ying-Chao ChouDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital at Linkou, Gueishan, Taiwan; Chang Gung University, Taoyuan, Taiwan.
Tsan-Wen HuangDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan; Chang Gung University, Taoyuan, Taiwan. Electronic address: b8601081@cgmh.org.tw.
Kuo-Chin HuangDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan; Chang Gung University, Taoyuan, Taiwan.
Hsin-Nung ShihDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital at Linkou, Gueishan, Taiwan; Chang Gung University, Taoyuan, Taiwan.
Mel S LeeDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital at Kaohsiung, Kaohsiung, Taiwan; Chang Gung University, Taoyuan, Taiwan.
Chang Gung University · TWChiayi Chang Gung Memorial Hospital · TWChang Gung Memorial Hospital · TWTaipei Medical University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoporotic intertrochanteric fractures often have postoperative complications despite a perfect reduction and an optimal fixation. We describe a simple technique using bone substitute augmentation and hypothesize that this method would prevent excessive sliding of the lag screw and potential subsequent complications.

methodsBetween January 2009 and July 2017, patients with osteoporotic intertrochanteric fractures who were treated with a dynamic hip screw (DHS) were enrolled in this retrospective cohort study. DHS group patients received conventional DHS treatment and BSA-DHS group patients received bone-substitute augmented DHS treatment. Factors such as demographics, Parker and Palmer mobility scores, health-related quality of life (HRQoL) scores (short-form Health Survey-12 Physical Component Summary [SF-12-PCS], and SF-12 Mental Component Summary [SF-12-MCS]), morbidities, mortality, and radiographic outcomes were compared.

resultsWe enrolled 85 patients: DHS group = 37 and BSA-DHS group = 48. There was significant lag-screw sliding (mean: 9 mm and 3 mm, p < 0.001), varus collapse (mean: 7° and 3°, p < 0.001), and femoral shortening (mean: 10 mm and 3 mm, p < 0.001) in the DHS group compared to the BSA-DHS group. The ability to get around the house was significantly different between the DHS and BSA-DHS groups (p = 0.031) at 3 months. Postoperative scores were not significantly different after 6, 9 or 12 months, however. Scores for the ability to get out of the house and to go shopping and the SF-12-PCS were significantly worse in the DHS group at 3 and 6 months. Malunion and lag-screw cutout were also significantly worse in the DHS group (p = 0.037 and p = 0.033, respectively).

conclusionsBone-substitute augmentation appears effective to prevent typical postoperative complications experienced by the DHS group patients, and to improve functional outcomes. Additional prospective randomized large-scale cohort studies are necessary to confirm this conclusion. LEVEL OF EVIDENCE: Therapeutic Level III.

Indexed as

Bone SubstitutesHip FracturesFracture Fixation, InternalFracture HealingHumansProspective StudiesQuality of LifeRetrospective StudiesTreatment OutcomeBone SubstitutesBone substituteHealth-related quality of life (HRQoL)Intertrochanteric fractureOsteoporosis

Identifiers

PMID35166210
PMCPMC8847843
OpenAlexW3027125605

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.