Evidence map›Paper›PMID 35166181›Full record

ArticleRenal failure2022

Prognosis and risk factors for cardiac valve calcification in Chinese end-stage kidney disease patients on combination therapy with hemodialysis and hemodiafiltration.

Jian-Qiong Xiong, Xue-Mei Chen, Chun-Ting Liang, Wen Guo, Bai-Li Wu, Xiao-Gang Du

Abstract read
In one paragraph

Article in Renal failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Serum Visfatin Level and Cardiac Valve Calcifcation in Hemodialysis Patients.Hemodialysis international. International Symposium on Home Hemodialysis · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jian-Qiong XiongDepartment of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xue-Mei ChenEmergency Department, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chun-Ting LiangDepartment of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Wen GuoEmergency Department, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Bai-Li WuEmergency Department, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiao-Gang DuDepartment of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0002-3445-0822

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac valve calcification (CVC) is an important risk factor for cardiovascular complications. However, limited data are available concerning the prevalence, clinical features and risk factors for CVC in end-stage kidney disease (ESKD) patients. In this study, we aimed to assess these parameters in Chinese ESKD patients receiving combination therapy with hemodialysis and hemodiafiltration.

methodsWe conducted a cross-sectional study on 293 ESKD patients undergoing combination therapy of hemodialysis and hemodiafiltration at the First Affiliated Hospital of Chongqing Medical University from October 2014 to December 2015. CVC was evaluated

resultsESKD patients with CVC had a higher prevalence of diabetes mellitus, aortic and/or coronary artery calcification, arrhythmia, heart failure and coronary heart disease; increased systolic, diastolic and pulse pressure; longer duration of hemodialysis and hypertension; reduced hemoglobin, albumin and high-density lipoprotein cholesterol levels; and increased serum calcium and calcium-phosphorus product levels compared with those without CVC. Logistic regression analysis showed that increased dialysis duration (

conclusionsCVC represents a common complication and a danger signal for cardiovascular events in ESKD patients undergoing combination therapy of hemodialysis and hemodiafiltration. The presence of diabetes, increased pulse pressure, long dialysis duration, hypoalbuminemia and high serum calcium levels were independent risk factors for CVC.

Indexed as

HemodiafiltrationAgedCalcinosisCalciumChinaCross-Sectional StudiesEchocardiographyFemaleHeart Valve DiseasesHumansKidney Failure, ChronicLogistic ModelsMaleMiddle AgedPrognosisRisk FactorsCalciumcardiac valve calcificationEnd-stage kidney diseasehemodiafiltrationhemodialysisvascular calcification

Identifiers

PMID35166181
PMCPMC8856035

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.