ArticleThoracic cancer2022
Microwave ablation via a flexible catheter for the treatment of nonsurgical peripheral lung cancer: A pilot study.
Article in Thoracic cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Transbronchial cryoablation in peripheral lung parenchyma with a novel thin cryoprobe and initial clinical testing.Thorax · 2024Trial
- Mid-term efficacy and safety of transbronchial cryoablation for stage IA peripheral lung cancer: a retrospective analysis.Translational lung cancer research · 2026Article
- Opportunities for Interventional Radiology in Transbronchial Interventions.Cardiovascular and interventional radiology · 2026Review
- Bronchoscopic ablation for non-small cell lung cancer.Journal of thoracic disease · 2025Review
- Global trends and academic landscapes of ultrasound applications in lung cancer research: a bibliometric analysis (2000-2024).Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
- Robotic-assisted and electromagnetic navigation bronchoscopy for multi-focal lung cancers: a narrative review.Translational lung cancer research · 2025Review
- Integrating Surgery and Ablative Therapies for the Management of Multiple Primary Lung Cancer: A Systematic Review.Cancers · 2025Review
- The role of interventional pulmonology in management of pulmonary nodules during lung cancer screening.Breathe (Sheffield, England) · 2025Review
- Comparative study of bronchoscopic and CT-guided percutaneous microwave ablation for inoperable non-small cell lung cancer.Translational lung cancer research · 2025Article
- Safety and efficacy of transbronchial radiofrequency ablation for stage IA peripheral lung cancer: a retrospective cohort study.Translational lung cancer research · 2025Article
- [Advances in the Treatment of Multiple Primary Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2025Review
- Review on endobronchial therapies-current status and future.Annals of translational medicine · 2024Review
- Interventional bronchoscopy in lung cancer treatment.Breathe (Sheffield, England) · 2024Review
- Ablation for Single Pulmonary Nodules, Primary or Metastatic. Εndobronchial Ablation Systems or Percutaneous.Journal of Cancer · 2024Article
- Review
- Advanced Imaging for Robotic Bronchoscopy: A Review.Diagnostics (Basel, Switzerland) · 2023Review
- Review
- Microwave ablation via a flexible catheter for the treatment of nonsurgical peripheral lung cancer: A pilot study.Thoracic cancer · 2022Article
- ERS International Congress 2020: highlights from the Clinical Techniques, Imaging and Endoscopy assembly.ERJ open research · 2021Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndobronchial microwave ablation via flexible catheter offers the potential for local therapy for inoperable peripheral lung cancer. The study aimed to evaluate the feasibility and safety of navigation bronchoscopy-guided water-cooled microwave ablation catheter for nonsurgical peripheral lung cancer.
methodsThis was a prospective single arm pilot study. Patients with early stage or multiple primary peripheral lung cancer who were nonsurgical candidates for surgery were enrolled in the study. Bronchoscopic microwave ablation was performed via a flexible water-cooled microwave ablation antenna under the guidance of navigation bronchoscopy. Radial probe endobronchial ultrasound combined with fluoroscopy was used to confirm the position. Treatment outcomes were evaluated based on follow-up chest CT and positron emission tomography scans. Primary endpoints were technical success and safety. Secondary endpoints were complete ablation rate, 2-year local control rate, and progression-free survival.
resultsThirteen patients were enrolled in the study from April 2018 to July 2019. A total of 19 sessions of microwave ablation were performed on 14 tumors under the guidance of navigation bronchoscopy. The technical success was 100%. Treatment-related complications occurred in two patients. The complete ablation rate was 78.6% (11/14). The 2-year local control rate was 71.4%. Median progression-free survival was 33 months for all patients.
conclusionsIn this pilot study, bronchoscopic microwave ablation appears to be feasible with acceptable occurrence of complication in the treatment of peripheral lung cancer under the guidance of navigation bronchoscopy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.