Evidence map›Paper›PMID 35165964›Full record

ArticleHuman brain mapping2022

Tracer-specific reference tissues selection improves detection of

Yanxiao Li, Yee Ling Ng, Manish D Paranjpe, Qi Ge, Fengyun Gu, Panlong Li, Shaozhen Yan, Jie Lu, Xiuying Wang, Yun Zhou and 1 more

Open access · goldAbstract read
In one paragraph

Article in Human brain mapping, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

  1. The clinical Alzheimer's disease spectrum classified in the A/T/N framework withEuropean journal of nuclear medicine and molecular imaging · 2026
    Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Cerebral Amyloid Deposition WithHuman brain mapping · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Comparison ofEJNMMI research · 2024
    Article
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Yanxiao LiCentral Research Institute, United Imaging Healthcare Group Co., Ltd, Shanghai, China.
Yee Ling NgCentral Research Institute, United Imaging Healthcare Group Co., Ltd, Shanghai, China.
Manish D ParanjpeHarvard-MIT Health Sciences and Technology Program, Harvard Medical School, Boston, Massachusetts, USA.
Qi GeCentral Research Institute, United Imaging Healthcare Group Co., Ltd, Shanghai, China.
Fengyun GuCentral Research Institute, United Imaging Healthcare Group Co., Ltd, Shanghai, China.
Panlong LiSchool of Electrical and Information Engineering, Zhengzhou University of Light Industry, Zhengzhou, Henan, China.
Shaozhen YanDepartment of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Jie LuDepartment of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-0425-3921
Xiuying WangSchool of Computer Science, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0001-7160-5929
Yun ZhouCentral Research Institute, United Imaging Healthcare Group Co., Ltd, Shanghai, China.ORCID 0000-0001-9135-336X
for the Alzheimer's Disease Neuroimaging Initiative
United Imaging Healthcare (China) · CNCapital Medical University · CNThe University of Sydney · AUHarvard University · USUniversity College Cork · IEZhengzhou University of Light Industry · CN

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
NIA NIH HHS U01 AG024904
6 · The paper itself

Abstract

This study sought to identify a reference tissue-based quantification approach for improving the statistical power in detecting changes in brain glucose metabolism, amyloid, and tau deposition in Alzheimer's disease studies. A total of 794, 906, and 903 scans were included for

Indexed as

Alzheimer DiseaseCognitive DysfunctionAmyloidAniline CompoundsBrainCarbolinesCross-Sectional StudiesEthylene GlycolsFluorodeoxyglucose F18GlucoseHumansPositron-Emission Tomography7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indoleAmyloidAniline CompoundsCarbolinesEthylene GlycolsflorbetapirFluorodeoxyglucose F18Glucose18F-FDG18F-florbetapir18F-flortaucipirAlzheimer's diseasereference tissue

Identifiers

PMID35165964
PMCPMC8996354
OpenAlexW4212948890

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.