Evidence map›Paper›PMID 35165928›Full record

ArticleHematological oncology2022

Chidamide with PEL regimen (prednisone, etoposide, lenalidomide) for elderly or frail patients with relapsed/refractory diffuse large B-Cell lymphoma -results of a single center, retrospective cohort in China.

Yawen Wang, Hongwei Xue, Wei Song, Shuxin Xiao, Fanjing Jing, Tieying Dong, Lili Wang

Open access · hybridAbstract read
In one paragraph

Article in Hematological oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yawen WangDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, China.ORCID https://orcid.org/0000-0003-3623-9235
Hongwei XueDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Wei SongDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Shuxin XiaoDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Fanjing JingDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Tieying DongDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Lili WangDepartment of Pathology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Qingdao University · CN

Funding

Beijing CSCO Clinical Oncology Research Foundation Programs Y-HR2018-270
6 · The paper itself

Abstract

Treatment for relapsed/refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL) is evolving rapidly due to the emergence of novel drugs, of which histone deacetylase inhibitors (HDACis) are an important example. This study showed efficacy in patients with R/R DLBCL after failure of conventional therapies. We conducted a single-center, retrospective study of 34 frail or elderly R/R DLBCL patients who had been treated off-label with chidamide-containing regimens from 2018 to 2020. X

Indexed as

Lymphoma, Large B-Cell, DiffuseLymphoma, Non-HodgkinAgedAminopyridinesAntineoplastic Combined Chemotherapy ProtocolsBenzamidesEtoposideFrail ElderlyHistone Deacetylase InhibitorsHumansLenalidomidePrednisoneRetrospective StudiesRituximabAminopyridinesBenzamidesEtoposideHistone Deacetylase InhibitorsLenalidomideN-(2-amino-5-fluorobenzyl)-4-(N-(pyridine-3-acrylyl)aminomethyl)benzamidePrednisoneRituximabchidamidehistone deacetylase inhibitorrefractory/relapsed diffuse large B-cell lymphomaretrospective study

Identifiers

PMID35165928
PMCPMC9790240
OpenAlexW4213013903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.