ArticleSleep & breathing = Schlaf & Atmung2022
Effect of CPAP on blood glucose fluctuation in patients with type 2 diabetes mellitus and obstructive sleep apnea.
Article in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Effects of continuous positive airway pressure therapy duration on patients with obstructive sleep apnoea and type 2 diabetes mellitus: a systematic review and meta-analysis.BMJ open respiratory research · 2026Pooled it
- Effects of continuous positive airway pressure therapy on glucose metabolism in patients with obstructive sleep apnoea and type 2 diabetes: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023Pooled it
- Obstructive sleep apnoea is associated with accelerated progression of diabetic kidney disease.Diabetic medicine : a journal of the British Diabetic Association · 2026Article
- Impact of continuous positive airway pressure therapy on metabolic and renal parameters in patients with obstructive sleep apnea, type 2 diabetes mellitus, and chronic kidney disease: a prospective cohort study.International urology and nephrology · 2026Article
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- A pilot study of high-intensity interval training and continuous positive airway pressure on vascular health in Thai adults with obesity, obstructive sleep apnea, and type 2 diabetes.Preventive medicine reports · 2025Article
- Exploring the Link Between Obstructive Sleep Apnea and Diabetes Mellitus: A Retrospective Single-Center Analysis.Biomedicines · 2025Article
- Continuous Glucose Monitoring Among People with and without Diabetes Mellitus and Sleep Apnoea.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Review
- Impact of Early Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio Decrease After Continuous Positive Airway Pressure on Glycaemic Control in Type 2 Diabetes with Obstructive Sleep Apnea.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Association of Positive Airway Pressure Adherence with Clinical Outcomes in Patients with Type 2 Diabetes and Obstructive Sleep Apnea.Diagnostics (Basel, Switzerland) · 2024Article
- Sleep Apnea, Obesity, and Diabetes - an Intertwined Trio.Current diabetes reports · 2023Review
- Recent Progress in Long-Term Sleep Monitoring Technology.Biosensors · 2023Review
- Risk of diabetes in patients with sleep apnea: comparison of surgery versus CPAP in a long-term follow-up study.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2023Article
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Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to investigate the effect of continuous positive airway pressure (CPAP) on blood glucose fluctuation in patients with type 2 diabetes mellitus (T2DM) and obstructive sleep apnea (OSA).
methodsPatients with T2DM and OSA were divided into an intervention group and a control group. All patients were treatment naïve. The intervention group was given CPAP therapy. The subjects were monitored using a continuous glucose monitoring system (CGMS) for 2 weeks.
resultsOf 60 patients, 30 were selected to receive CPAP intervention while 30 without CPAP served as controls. The CPAP tolerance of the intervention group was good, with average time on CPAP therapy of 55.2 ± 4.3 days, and average daily time on CPAP therapy of 8.3 ± 2.8 h. The postprandial blood glucose (PBG), fasting blood glucose (FBG), and HbA1c levels in the intervention group decreased significantly (P < 0.05). Significant variations in 24-h mean blood glucose and night-time mean blood glucose were significantly lower with CPAP therapy than without therapy (P < 0.05, respectively). The mean of daily differences and mean ambulatory glucose excursions were both considerably lower with treatment than without (P < 0.05, respectively). There was also a significant difference in time in range and time above range (P < 0.05, respectively).
conclusionCPAP treatment may significantly improve the blood glucose level and blood glucose stability in patients with T2DM and OSA. CPAP is an effective treatment method beyond lifestyle intervention and drug therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.