ReviewJournal of assisted reproduction and genetics2022
Maternal effect factors that contribute to oocytes developmental competence: an update.
Review in Journal of assisted reproduction and genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Scanning the Meiotic Spindle in Assisted Reproductive Techniques to Assess Oocyte Quality and Embryo Ploidy Evaluated by Artificial Intelligence (SMARTAI Study)
Scanning the Meiotic Spindle in Assisted Reproductive Techniques to Assess Oocyte Quality (SMART Study)
Who cites it
28 citing papers in PubMed.
- Strain- and lineage-specific regulation of lipid droplet metabolism in the mouse blastocyst†.Biology of reproduction · 2026Article
- A multidimensional follicular profile integrating oxidative stress, apoptosis and PI3K/AKT/mTOR signaling in relation to oocyte developmental competence in in vitro fertilization cycles.Journal of assisted reproduction and genetics · 2026Article
- Fertilization time and oocyte spindle integrity: implication for embryo ploidy.Reproduction & fertility · 2026Article
- Loss of the maternal effect gene NLRP2 impairs embryonic and extra-embryonic development, revealing a novel genetic cause of congenital anomalies†.Biology of reproduction · 2026Article
- THAP1 is a maternal effect factor required for the first cell cycle via Rrm1 in early mouse embryos.EMBO reports · 2026Article
- Transcription Factor TCF12-Mediated Maternal Gene Expressions in Mouse Oocyte Are Prerequisites of Successful Fertilisation and Zygotic Genome Activation.Cell proliferation · 2026Article
- Rates and risk factors of oocyte immaturity: toward personalized selection for rescue in vitro maturation.Journal of assisted reproduction and genetics · 2026Article
- Newly Evolved Endogenous Retroviruses Prime the Ovarian Reserve for Activation.Research square · 2025Article
- Newly Evolved Endogenous Retroviruses Prime the Ovarian Reserve for Activation.bioRxiv : the preprint server for biology · 2025Article
- Cannabis impacts female fertility as evidenced by an in vitro investigation and a case-control study.Nature communications · 2025Article
- Rescue in vitro maturation of germinal vesicle oocytes after ovarian stimulation: the importance of the culture media.Human reproduction (Oxford, England) · 2025Article
- In vitro gametogenesis: Towards competent oocytes: Limitations and future improvements for generating oocytes from pluripotent stem cells in culture.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025Review
- The chromatin accessibility landscape of mouse oocytes during configuration transition.Cell proliferation · 2025Article
- Spatial distribution of maternal factors in pig mature oocytes.Animal biotechnology · 2024Article
- Stereological study of organelle distribution in human mature oocytes.Scientific reports · 2024Article
- The subcortical maternal complex modulates the cell cycle during early mammalian embryogenesis via 14-3-3.Nature communications · 2024Article
- Longitudinal profiling of human androgenotes through single-cell analysis unveils paternal gene expression dynamics in early embryo development.Human reproduction (Oxford, England) · 2024Article
- Extracellular vesicles secreted by cumulus cells contain microRNAs that are potential regulatory factors of mouse oocyte developmental competence.Molecular human reproduction · 2024Article
- [Analysis of Risk Factors for Recurrent Pregnancy Loss in Patients UndergoingSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Article
- Surfeit locus protein 4 modulates endoplasmic reticulum function and maintains oocyte quality.Cell cycle (Georgetown, Tex.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oocyte developmental competence is defined as the capacity of the female gamete to be fertilized and sustain development to the blastocyst stage. Epigenetic reprogramming, a correct cell division pattern, and an efficient DNA damage response are all critical events that, before embryonic genome activation, are governed by maternally inherited factors such as maternal-effect gene (MEG) products. Although these molecules are stored inside the oocyte until ovulation and exert their main role during fertilization and preimplantation development, some of them are already functioning during folliculogenesis and oocyte meiosis resumption. This mini review summarizes the crucial roles played by MEGs during oocyte maturation, fertilization, and preimplantation development with a direct/indirect effect on the acquisition or maintenance of oocyte competence. Our aim is to inspire future research on a topic with potential clinical perspectives for the prediction and treatment of female infertility.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.