Evidence map›Paper›PMID 35165525›Full record

ArticleInternational journal of medical sciences2022

Potential Genes Associated with COVID-19 and Comorbidity.

Shanshan Feng, Fuqiang Song, Wenqiong Guo, Jishan Tan, Xianqin Zhang, Fengling Qiao, Jinlin Guo, Lin Zhang, Xu Jia

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 43 citations in OpenAlex.

  1. Improved Cardiac Function and Glycemic Control in Elderly Diabetic Patients Through Structured Case Management After CABG.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Trial
  2. Review
  3. Article
  4. Analyses of haplotypes ofFrontiers in genetics · 2025
    Article
  5. Article
  6. Alterations in CX3CL1 Levels and Its Role in Viral Pathogenesis.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Association of specificFrontiers in immunology · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. The immunogenetics of COVID-19.Immunogenetics · 2023
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Shanshan FengCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Fuqiang SongDepartment of medical Laboratory, The General Hospital of Western Theater Command, Chengdu, China.
Wenqiong GuoChengdu Medical College, Chengdu, China.
Jishan TanDepartment of medical Laboratory, The General Hospital of Western Theater Command, Chengdu, China.
Xianqin ZhangSchool of Basic Medical Sciences, Chengdu Medical College, Chengdu, Sichuan, China.
Fengling QiaoCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Jinlin GuoKey Laboratory of Systematic Research of Distinctive Chinese Medicine Resources in Southwest China, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Lin ZhangDepartment of Pharmacy, Shaoxing People's Hospital, Shaoxing Hospital, Zhejiang University School of Medicine, Shaoxing, China.
Xu JiaNon-coding RNA and Drug Discovery Key Laboratory of Sichuan Province, Chengdu Medical College, Chengdu, Sichuan, China.
Chengdu Medical College · CNChengdu University of Traditional Chinese Medicine · CNShaoxing People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension, diabetes mellitus, and coronary artery disease are common comorbidities and dangerous factors for infection and serious COVID-19. Polymorphisms in genes associated with comorbidities may help observe susceptibility and disease severity variation. However, specific genetic factors and the extent to which they can explain variation in susceptibility of severity are unclear. Therefore, we evaluated candidate genes associated with COVID-19 and hypertension, diabetes mellitus, and coronary artery disease. In particular, we performed searches against OMIM, NCBI, and other databases, protein-protein interaction network construction, and GO and KEGG pathway enrichment analyses. Results showed that the associated overlapping genes were

Indexed as

ComorbidityCoronary Artery DiseaseCOVID-19Diabetes ComplicationsHumansHypertensionMutationProtein Interaction MapsbioinformaticscomorbidityCOVID-19disease severitySARS-CoV-2susceptibility gene

Identifiers

PMID35165525
PMCPMC8795808
OpenAlexW4210567477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.